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I-branching N-acetylglucosaminyltransferase regulates prostate cancer invasiveness by enhancing 51 integrin signaling
Jotaro Mikami et al.
CANCER SCIENCE (2016)
Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer
Justin M. Drake et al.
CELL (2016)
E2 enzymes: more than just middle men
Mikaela D. Stewart et al.
CELL RESEARCH (2016)
被撤回的出版物: TRIM16 suppresses the progression of prostate tumors by inhibiting the Snail signaling pathway (Retracted article. See vol. 51, 2023)
Li Qi et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2016)
MicroRNA-424 impairs ubiquitination to activate STAT3 and promote prostate tumor progression
Cecilia Dallavalle et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
UHRF1 overexpression is involved in cell proliferation and biochemical recurrence in prostate cancer after radical prostatectomy
Xuechao Wan et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2016)
Hypoacetylation, hypomethylation, and dephosphorylation of H2B histones and excessive histone deacetylase activity in DU-145 prostate cancer cells
Shundong Cang et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2016)
Depletion of SAG/RBX2 E3 ubiquitin ligase suppresses prostate tumorigenesis via inactivation of the PI3K/AKT/mTOR axis
Mingjia Tan et al.
MOLECULAR CANCER (2016)
Pharmacological targeting of CXCL12/CXCR4 signaling in prostate cancer bone metastasis
M. Katie Conley-LaComb et al.
MOLECULAR CANCER (2016)
KAT8 Regulates Androgen Signaling in Prostate Cancer Cells
Ji-Young Kim et al.
MOLECULAR ENDOCRINOLOGY (2016)
The role of glycans in the development and progression of prostate cancer
Jennifer Munkley et al.
NATURE REVIEWS UROLOGY (2016)
Restoration of tumor suppression in prostate cancer by targeting the E3 ligase E6AP
P. J. Paul et al.
ONCOGENE (2016)
Skp2 is associated with paclitaxel resistance in prostate cancer cells
Yeguo Yang et al.
ONCOLOGY REPORTS (2016)
Regulating NKX3.1 stability and function: Post-translational modifications and structural determinants
Achuth Padmanabhan et al.
PROSTATE (2016)
Phosphoproteome analysis demonstrates the potential role of THRAP3 phosphorylation in androgen-independent prostate cancer cell growth
Yoko Ino et al.
PROTEOMICS (2016)
Pyruvate dehydrogenase alpha 1 as a target of omega-3 polyunsaturated fatty acids in human prostate cancer through a global phosphoproteomic analysis
Heng Zhao et al.
PROTEOMICS (2016)
Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer
Akash K. Kaushik et al.
NATURE COMMUNICATIONS (2016)
SENP1 regulates PTEN stability to dictate prostate cancer development
Tasneem Bawa-Khalfe et al.
Oncotarget (2016)
PC-1 works in conjunction with E3 ligase CHIP to regulate androgen receptor stability and activity
Jian Wang et al.
ONCOTARGET (2016)
The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2-dependent ITCH/AIP4 activation
Christophe Le Clorennec et al.
ONCOTARGET (2016)
The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer
Shan Wang et al.
ONCOTARGET (2016)
SIRT1 and LSD1 competitively regulate KU70 functions in DNA repair and mutation acquisition in cancer cells
Mendel Roth et al.
ONCOTARGET (2016)
Inhibition of O-GlcNAc transferase activity reprograms prostate cancer cell metabolism
Harri M. Itkonen et al.
ONCOTARGET (2016)
SUMOylation of TBL1 and TBLR1 promotes androgen-independent prostate cancer cell growth
Soo-Yeon Park et al.
ONCOTARGET (2016)
Regulation of tumor suppressor EAF2 polyubiquitination by ELL1 and SIAH2 in prostate cancer cells
Xinpei Yu et al.
ONCOTARGET (2016)
ST6Gal-I overexpression facilitates prostate cancer progression via the PI3K/Akt/GSK-3β/β-catenin signaling pathway
Anwen Wei et al.
ONCOTARGET (2016)
Acetylation of androgen receptor by ARD1 promotes dissociation from HSP90 complex and prostate tumorigenesis
John S. DePaolo et al.
ONCOTARGET (2016)
Mesenchymal stem cells overexpressing Sirt1 inhibit prostate cancer growth by recruiting natural killer cells and macrophages
Yang Yu et al.
ONCOTARGET (2016)
Loss of miR-449a in ERG-associated prostate cancer promotes the invasive phenotype by inducing SIRT1
Parameet Kumar et al.
ONCOTARGET (2016)
P300 acetyltransferase regulates fatty acid synthase expression, lipid metabolism and prostate cancer growth
Xiaokun Gang et al.
ONCOTARGET (2016)
Improvement of Prostate Cancer Diagnosis by Detecting PSA Glycosylation-Specific Changes
Esther Llop et al.
THERANOSTICS (2016)
Effect of SIRT1 Gene on Epithelial-Mesenchymal Transition of Human Prostate Cancer PC-3 Cells
Ying Cui et al.
MEDICAL SCIENCE MONITOR (2016)
MDM2 Inhibition Sensitizes Prostate Cancer Cells to Androgen Ablation and Radiotherapy in a p53-Dependent Manner
Felix Y. Feng et al.
NEOPLASIA (2016)
Glycosylation is an Androgen-Regulated Process Essential for Prostate Cancer Cell Viability
Jennifer Munkley et al.
EBIOMEDICINE (2016)
Loss of Sirt1 Promotes Prostatic Intraepithelial Neoplasia, Reduces Mitophagy, and Delays Park2 Translocation to Mitochondria
Gabriele Di Sante et al.
AMERICAN JOURNAL OF PATHOLOGY (2015)
Resveratrol regulates PTEN/Akt pathway through inhibition of MTA1/HDAC unit of the NuRD complex in prostate cancer
Swati Dhar et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2015)
TRAF6 promotes TGFβ-induced invasion and cell-cycle regulation via Lys63-linked polyubiquitination of Lys178 in TGFβ type I receptor
Reshma Sundar et al.
CELL CYCLE (2015)
Targeting geranylgeranylation reduces adrenal gland tumor burden in a murine model of prostate cancer metastasis
Jacqueline E. Reilly et al.
CLINICAL & EXPERIMENTAL METASTASIS (2015)
Implications of ubiquitin ligases in castration-resistant prostate cancer
Jianfei Qi et al.
CURRENT OPINION IN ONCOLOGY (2015)
MPP8 and SIRT1 crosstalk in E-cadherin gene silencing and epithelial-mesenchymal transition
Lidong Sun et al.
EMBO REPORTS (2015)
EGFR and IGF-1R in regulation of prostate cancer cell phenotype and polarity: opposing functions and modulation by T-cadherin
Kseniya Maslova et al.
FASEB JOURNAL (2015)
Pc2-mediated SUMOylation of WWOX is essential for its suppression of DU145 prostate tumorigenesis
Hye-Jin Choi et al.
FEBS LETTERS (2015)
Roles of Ubiquitination and SUMOylation on Prostate Cancer: Mechanisms and Clinical Implications
Zhenbang Chen et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
MDC1 functionally identified as an androgen receptor co-activator participates in suppression of prostate cancer
Chunyu Wang et al.
NUCLEIC ACIDS RESEARCH (2015)
Androgens Regulate SMAD Ubiquitination Regulatory Factor-1 Expression and Prostate Cancer Cell Invasion
Xiaokun Gang et al.
PROSTATE (2015)
A bivalent role of TIP60 histone acetyl transferase in human cancer
Gaelle Judes et al.
EPIGENOMICS (2015)
Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity
Toshiaki Fukushima et al.
NATURE COMMUNICATIONS (2015)
E2F1 enhances glycolysis through suppressing Sirt6 transcription in cancer cells
Minghui Wu et al.
ONCOTARGET (2015)
SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination
Wenfu Lu et al.
ONCOTARGET (2015)
Elevated expression of UBE2T exhibits oncogenic properties in human prostate cancer
Mingxin Wen et al.
ONCOTARGET (2015)
AR-v7 protein expression is regulated by protein kinase and phosphatase
Yinan Li et al.
ONCOTARGET (2015)
SIRT3 inhibits prostate cancer by destabilizing oncoprotein c-MYC through regulation of the PI3K/Akt pathway
Yizhou Quan et al.
ONCOTARGET (2015)
The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer
Jennifer Munkley et al.
ONCOTARGET (2015)
SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors
Shivani Malik et al.
SCIENTIFIC REPORTS (2015)
Amino Acid Activation of mTORC1 by a PB1-Domain-Driven Kinase Complex Cascade
Juan F. Linares et al.
CELL REPORTS (2015)
SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase
Hengrui Zhu et al.
CELL REPORTS (2015)
Dichotomy in the Epigenetic Mark Lysine Acetylation is Critical for the Proliferation of Prostate Cancer Cells
Ravi Pathak et al.
CANCERS (2015)
Advances in the development of SUMO specific protease (SENP) inhibitors
Ashutosh Kumar et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2015)
Interruption of KLF5 acetylation converts its function from tumor suppressor to tumor promoter in prostate cancer cells
Xin Li et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
p53 Mutation Directs AURKA Overexpression via miR-25 and FBXW7 in Prostatic Small Cell Neuroendocrine Carcinoma
Zhen Li et al.
MOLECULAR CANCER RESEARCH (2015)
SUMO ligase PIAS1 functions as a target gene selective androgen receptor coregulator on prostate cancer cell chromatin
Sari Toropainen et al.
NUCLEIC ACIDS RESEARCH (2015)
STRING v10: protein-protein interaction networks, integrated over the tree of life
Damian Szklarczyk et al.
NUCLEIC ACIDS RESEARCH (2015)
In vivo quantitative phosphoproteomic profiling identifies novel regulators of castration-resistant prostate cancer growth
N. Jiang et al.
ONCOGENE (2015)
The E3 ubiquitin ligase NEDD4 negatively regulates HER3/ErbB3 level and signaling
Z. Huang et al.
ONCOGENE (2015)
Glycosylation in cancer: mechanisms and clinical implications
Salome S. Pinho et al.
NATURE REVIEWS CANCER (2015)
RBR E3 ubiquitin ligases: new structures, new insights, new questions
Donald E. Spratt et al.
BIOCHEMICAL JOURNAL (2014)
CBP Loss Cooperates with PTEN Haploinsufficiency to Drive Prostate Cancer: Implications for Epigenetic Therapy
Liya Ding et al.
CANCER RESEARCH (2014)
p300 Acetyltransferase Regulates Androgen Receptor Degradation and PTEN-Deficient Prostate Tumorigenesis
Jian Zhong et al.
CANCER RESEARCH (2014)
Fbxo45-mediated degradation of the tumor-suppressor Par-4 regulates cancer cell survival
X. Chen et al.
CELL DEATH AND DIFFERENTIATION (2014)
Androgen receptor phosphorylation: biological context and functional consequences
Yulia Koryakina et al.
ENDOCRINE-RELATED CANCER (2014)
Tyrosine kinase inhibitors in the treatment of prostate cancer: taking the next step in clinical development
Michelle A. Ojemuyiwa et al.
EXPERT OPINION ON EMERGING DRUGS (2014)
Important Role of SUMOylation of Spliceosome Factors in Prostate Cancer Cells
Donghua Wen et al.
JOURNAL OF PROTEOME RESEARCH (2014)
Differential Requirement for Src Family Tyrosine Kinases in the Initiation, Progression, and Metastasis of Prostate Cancer
Irwin H. Gelman et al.
MOLECULAR CANCER RESEARCH (2014)
Phosphoproteomic Profiling Identifies Focal Adhesion Kinase as a Mediator of Docetaxel Resistance in Castrate-Resistant Prostate Cancer
Brian Y. Lee et al.
MOLECULAR CANCER THERAPEUTICS (2014)
Coactivator MYST1 Regulates Nuclear Factor-κB and Androgen Receptor Functions During Proliferation of Prostate Cancer Cells
Anbalagan Jaganathan et al.
MOLECULAR ENDOCRINOLOGY (2014)
The Von Hippel-Lindau Protein Suppresses Androgen Receptor Activity
Jing Wang et al.
MOLECULAR ENDOCRINOLOGY (2014)
Nuclear Mobility and Activity of FOXA1 with Androgen Receptor Are Regulated by SUMOylation
Paivi Sutinen et al.
MOLECULAR ENDOCRINOLOGY (2014)
Slug regulates E-cadherin repression via p19Arf in prostate tumorigenesis
Yingqiu Xie et al.
MOLECULAR ONCOLOGY (2014)
REST mediates androgen receptor actions on gene repression and predicts early recurrence of prostate cancer
Charlotte Svensson et al.
NUCLEIC ACIDS RESEARCH (2014)
SUMOylation modulates the transcriptional activity of androgen receptor in a target gene and pathway selective manner
Paivi Sutinen et al.
NUCLEIC ACIDS RESEARCH (2014)
Androgen receptor degradation by the E3 ligase CHIP modulates mitotic arrest in prostate cancer cells
S. Sarkar et al.
ONCOGENE (2014)
Skp2 Regulates Androgen Receptor Through Ubiquitin-Mediated Degradation Independent of Akt/mTOR Pathways in Prostate Cancer
Bo Li et al.
PROSTATE (2014)
Ubiquitylome analysis identifies dysregulation of effector substrates in SPOP-mutant prostate cancer
Jean-Philippe P. Theurillat et al.
SCIENCE (2014)
TRAF6 Stimulates the Tumor-Promoting Effects of TGFβ Type I Receptor Through Polyubiquitination and Activation of Presenilin 1
Shyam Kumar Gudey et al.
SCIENCE SIGNALING (2014)
Statins: protectors or pretenders in prostate cancer?
Hyeongsun Moon et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)
CXCL12/CXCR4 signaling counteracts docetaxel-induced microtubule stabilization via p21-activated kinase 4-dependent activation of LIM domain kinase 1
Arun Bhardwaj et al.
ONCOTARGET (2014)
The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growth
Yuh-Shyan Tsai et al.
ONCOTARGET (2014)
PIAS1 is a crucial factor for prostate cancer cell survival and a valid target in docetaxel resistant cells
Martin Puhr et al.
ONCOTARGET (2014)
TUSC3 Loss Alters the ER Stress Response and Accelerates Prostate Cancer Growth in vivo
Peter Horak et al.
SCIENTIFIC REPORTS (2014)
Rational design and validation of a Tip60 histone acetyltransferase inhibitor
Chunxia Gao et al.
SCIENTIFIC REPORTS (2014)
Glycans - the third revolution in evolution
Gordan Lauc et al.
FRONTIERS IN GENETICS (2014)
Human fucosyltransferase 6 enables prostate cancer metastasis to bone
J. Li et al.
BRITISH JOURNAL OF CANCER (2013)
Skp2 Deletion Unmasks a p27 Safeguard that Blocks Tumorigenesis in the Absence of pRb and p53 Tumor Suppressors
Hongling Zhao et al.
CANCER CELL (2013)
The E3 Ubiquitin Ligase Siah2 Contributes to Castration-Resistant Prostate Cancer by Regulation of Androgen Receptor Transcriptional Activity
Jianfei Qi et al.
CANCER CELL (2013)
E3 Ubiquitin Ligase RNF126 Promotes Cancer Cell Proliferation by Targeting the Tumor Suppressor p21 for Ubiquitin-Mediated Degradation
Xu Zhi et al.
CANCER RESEARCH (2013)
A Gain-of-Function Mutation in DHT Synthesis in Castration-Resistant Prostate Cancer
Kai-Hsiung Chang et al.
CELL (2013)
HDAC11 is a novel drug target in carcinomas
Hedwig E. Deubzer et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
Loss of SUMOylation on ATF3 Inhibits Proliferation of Prostate Cancer Cells by Modulating CCND1/2 Activity
Chiung-Min Wang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Posttranslational Modification of the Androgen Receptor in Prostate Cancer
Travis van der Steen et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Estrogen Receptor β (ERβ1) Transactivation Is Differentially Modulated by the Transcriptional Coregulator Tip60 in a cis-Acting Element-dependent Manner
Ming-Tsung Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Phosphorylation of NuMA by Aurora-A kinase in PC-3 prostate cancer cells affects proliferation, survival, and interphase NuMA localization
Raheleh Toughiri et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2013)
Id4 dependent acetylation restores mutant-p53 transcriptional activity
Ashley E. Knowell et al.
MOLECULAR CANCER (2013)
Targeting IGF-IR with Ganitumab Inhibits Tumorigenesis and Increases Durability of Response to Androgen-Deprivation Therapy in VCaP Prostate Cancer Xenografts
Cale D. Fahrenholtz et al.
MOLECULAR CANCER THERAPEUTICS (2013)
Core2 O-glycan-expressing prostate cancer cells are resistant to NK cell immunity
Teppei Okamoto et al.
MOLECULAR MEDICINE REPORTS (2013)
SUMO-specific protease 1 promotes prostate cancer progression and metastasis
Q. Wang et al.
ONCOGENE (2013)
Ubiquitin-Proteasome Pathway and Prostate Cancer
Fang-Zhi Chen et al.
ONKOLOGIE (2013)
BIRC6 Protein, an Inhibitor of Apoptosis: Role in Survival of Human Prostate Cancer Cells
Christopher G. Low et al.
PLOS ONE (2013)
Different Expression Patterns and Functions of Acetylated and Unacetylated Klf5 in the Proliferation and Differentiation of Prostatic Epithelial Cells
Changsheng Xing et al.
PLOS ONE (2013)
Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets
Justin M. Drake et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
SIRT1 enhances matrix metalloproteinase-2 expression and tumor cell invasion in prostate cancer cells
Jenna D. Lovaas et al.
PROSTATE (2013)
Cycles of Ubiquitination and Deubiquitination Critically Regulate Growth Factor-Mediated Activation of Akt Signaling
Wei-Lei Yang et al.
SCIENCE SIGNALING (2013)
Inhibition of tumor growth and histopathological changes following treatment with a chemokine receptor CXCR4 antagonist in a prostate cancer xenograft model
Kang Su Cho et al.
ONCOLOGY LETTERS (2013)
Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer
Tiago Baptista et al.
ONCOTARGET (2013)
SCFβ-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration
Jiateng Zhong et al.
ONCOTARGET (2013)
Inhibition of SIRT6 in prostate cancer reduces cell viability and increases sensitivity to chemotherapeutics
Yewei Liu et al.
PROTEIN & CELL (2013)
Mitochondrial DNA depletion sensitizes cancer cells to PARP inhibitors by translational and post-translational repression of BRCA2
A. A. Arbini et al.
ONCOGENESIS (2013)
KLF6 Loss of Function in Human Prostate Cancer Progression Is Implicated in Resistance to Androgen Deprivation
XiaoMei Liu et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Acetylation-Dependent Regulation of Skp2 Function
Hiroyuki Inuzuka et al.
CELL (2012)
Systemic Delivery of Oncolytic Adenoviruses Targeting Transforming Growth Factor-β Inhibits Established Bone Metastasis in a Prostate Cancer Mouse Model
Zebin Hu et al.
HUMAN GENE THERAPY (2012)
Inhibition of cortactin and SIRT1 expression attenuates migration and invasion of prostate cancer DU145 cells
Keita Nakane et al.
INTERNATIONAL JOURNAL OF UROLOGY (2012)
Polyubiquitination of Transforming Growth Factor β (TGFβ)-associated Kinase 1 Mediates Nuclear Factor-κB Activation in Response to Different Inflammatory Stimuli
Anahita Hamidi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Selective Roles for cAMP Response Element-binding Protein Binding Protein and p300 Protein as Coregulators for Androgen-regulated Gene Expression in Advanced Prostate Cancer Cells
Irina Ianculescu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The in Vivo Role of Androgen Receptor SUMOylation as Revealed by Androgen Insensitivity Syndrome and Prostate Cancer Mutations Targeting the Proline/Glycine Residues of Synergy Control Motifs
Sarmistha Mukherjee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The Chaperone-assisted E3 Ligase C Terminus of Hsc70-interacting Protein (CHIP) Targets PTEN for Proteasomal Degradation
Syed Feroj Ahmed et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
HECT and RING finger families of E3 ubiquitin ligases at a glance
Meredith B. Metzger et al.
JOURNAL OF CELL SCIENCE (2012)
Regulation of the androgen receptor by post-translational modifications
Kelly Coffey et al.
JOURNAL OF ENDOCRINOLOGY (2012)
Dynamic SUMOylation Is Linked to the Activity Cycles of Androgen Receptor in the Cell Nucleus
Miia Rytinki et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
The CXCL12/CXCR4 axis promotes ligand-independent activation of the androgen receptor
Sathish Kasina et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2012)
Histone H2B ubiquitin ligases RNF20 and RNF40 in androgen signaling and prostate cancer cell growth
Tiina Jaaskelainen et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2012)
Proteoglycans in prostate cancer
Iris J. Edwards
NATURE REVIEWS UROLOGY (2012)
Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation
F. Wang et al.
ONCOGENE (2012)
The SRA protein UHRF1 promotes epigenetic crosstalks and is involved in prostate cancer progression
F. Babbio et al.
ONCOGENE (2012)
SIRT1 induces EMT by cooperating with EMT transcription factors and enhances prostate cancer cell migration and metastasis
V. Byles et al.
ONCOGENE (2012)
Combined Inhibition of IGF-1R/IR and Src Family Kinases Enhances Antitumor Effects in Prostate Cancer by Decreasing Activated Survival Pathways
Farshid Dayyani et al.
PLOS ONE (2012)
Characterisation of a Tip60 Specific Inhibitor, NU9056, in Prostate Cancer
Kelly Coffey et al.
PLOS ONE (2012)
Forkhead Box Protein A2 (FOXA2) Protein Stability and Activity Are Regulated by Sumoylation
Narasimhaswamy S. Belaguli et al.
PLOS ONE (2012)
Inactivation of androgen-induced regulator ARD1 inhibits androgen receptor acetylation and prostate tumorigenesis
Zehua Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression
Justin M. Drake et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The ubiquitin-proteasome system in prostate cancer and its transition to castration resistance
Ioannis A. Voutsadakis et al.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2012)
SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane
Jian Huang et al.
NATURE COMMUNICATIONS (2012)
CAND1 Promotes PLK4-Mediated Centriole Overduplication and Is Frequently Disrupted in Prostate Cancer
Nina Korzeniewski et al.
NEOPLASIA (2012)
The Role of the Small Ubiquitin-Related Modifier (SUMO) Pathway in Prostate Cancer
Panagiotis J. Vlachostergios et al.
BIOMOLECULES (2012)
Involvement of HDAC1 in E-cadherin expression in prostate cancer cells; its implication for cell motility and invasion
Nam Hyun Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
E3 ubiquitin protein ligase, E6-associated protein (E6-AP) regulates PI3K-Akt signaling and prostate cell growth
Sathish Srinivasan et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2011)
A Cullin3-KLHL20 Ubiquitin Ligase-Dependent Pathway Targets PML to Potentiate HIF-1 Signaling and Prostate Cancer Progression
Wei-Chien Yuan et al.
CANCER CELL (2011)
Disruption of a Sirt1-Dependent Autophagy Checkpoint in the Prostate Results in Prostatic Intraepithelial Neoplasia Lesion Formation
Michael J. Powell et al.
CANCER RESEARCH (2011)
The IL-8-Regulated Chemokine Receptor CXCR7 Stimulates EGFR Signaling to Promote Prostate Cancer Growth
Rajendra Kumar Singh et al.
CANCER RESEARCH (2011)
Nuclear PTEN Regulates the APC-CDH1 Tumor-Suppressive Complex in a Phosphatase-Independent Manner
Min Sup Song et al.
CELL (2011)
Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH
Perry A. Christian et al.
MOLECULAR CANCER (2011)
Loss of PTEN Permits CXCR4-Mediated Tumorigenesis through ERK1/2 in Prostate Cancer Cells
Mahandranauth A. Chetram et al.
MOLECULAR CANCER RESEARCH (2011)
Inhibition of the Acetyltransferases p300 and CBP Reveals a Targetable Function for p300 in the Survival and Invasion Pathways of Prostate Cancer Cell Lines
Frederic R. Santer et al.
MOLECULAR CANCER THERAPEUTICS (2011)
FOXP3 Orchestrates H4K16 Acetylation and H3K4 Trimethylation for Activation of Multiple Genes by Recruiting MOF and Causing Displacement of PLU-1
Hiroto Katoh et al.
MOLECULAR CELL (2011)
Peptide Switch Is Essential for Sirt1 Deacetylase Activity
Hyeog Kang et al.
MOLECULAR CELL (2011)
Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth
Lei Lv et al.
MOLECULAR CELL (2011)
COP1 is a tumour suppressor that causes degradation of ETS transcription factors
Alberto C. Vitari et al.
NATURE (2011)
Inhibition of androgen receptor activity by histone deacetylase 4 through receptor SUMOylation
Y. Yang et al.
ONCOGENE (2011)
Differential transformation capacity of Src family kinases during the initiation of prostate cancer
Houjian Cai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Transcriptional Coactivators p300 and CBP Stimulate Estrogen Receptor-Beta Signaling and Regulate Cellular Events in Prostate Cancer
Jan Bouchal et al.
PROSTATE (2011)
Statins Reduce the Androgen Sensitivity and Cell Proliferation by Decreasing the Androgen Receptor Protein in Prostate Cancer Cells
Akira Yokomizo et al.
PROSTATE (2011)
Proteome-wide post-translational modification statistics: frequency analysis and curation of the swiss-prot database
George A. Khoury et al.
SCIENTIFIC REPORTS (2011)
Siah2-Dependent Concerted Activity of HIF and FoxA2 Regulates Formation of Neuroendocrine Phenotype and Neuroendocrine Prostate Tumors
Jianfei Qi et al.
CANCER CELL (2010)
Global Levels of Specific Histone Modifications and an Epigenetic Gene Signature Predict Prostate Cancer Progression and Development
Tina Bianco-Miotto et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2010)
Atorvastatin and Celecoxib in Combination Inhibits the Progression of Androgen-Dependent LNCaP Xenograft Prostate Tumors to Androgen Independence
Xi Zheng et al.
CANCER PREVENTION RESEARCH (2010)
Fibroblast Growth Factor Receptor 4 Regulates Tumor Invasion by Coupling Fibroblast Growth Factor Signaling to Extracellular Matrix Degradation
Nami Sugiyama et al.
CANCER RESEARCH (2010)
Inhibition of GGTase-I and FTase disrupts cytoskeletal organization of human PC-3 prostate cancer cells
Sanna S. Virtanen et al.
CELL BIOLOGY INTERNATIONAL (2010)
Rosuvastatin, Identified From a Zebrafish Chemical Genetic Screen for Antiangiogenic Compounds, Suppresses the Growth of Prostate Cancer
Chunyang Wang et al.
EUROPEAN UROLOGY (2010)
Resveratrol enhances p53 acetylation and apoptosis in prostate cancer by inhibiting MTA1/NuRD complex
Li Kai et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
SENP1 Induces Prostatic Intraepithelial Neoplasia through Multiple Mechanisms
Tasneem Bawa-Khalfe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Heat Shock Protein 27 Is Required for Sex Steroid Receptor Trafficking to and Functioning at the Plasma Membrane
Mahnaz Razandi et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence
Hui-Kuan Lin et al.
NATURE (2010)
β-TrCP Inhibition Reduces Prostate Cancer Cell Growth via Upregulation of the Aryl Hydrocarbon Receptor
Udi Gluschnaider et al.
PLOS ONE (2010)
Tip60 Promotes Prostate Cancer Cell Proliferation by Translocation of Androgen Receptor into the Nucleus
Masaki Shiota et al.
PROSTATE (2010)
Statin-Induced Autophagy by Inhibition of Geranylgeranyl Biosynthesis in Prostate Cancer PC3 Cells
Ankur Parikh et al.
PROSTATE (2010)
EGFR Targeting in Hormone-Refractory Prostate Cancer: Current Appraisal and Prospects for Treatment
Olivier Guerin et al.
PHARMACEUTICALS (2010)
Kinase-Dependent and -Independent Roles of EphA2 in the Regulation of Prostate Cancer Invasion and Metastasis
Maria Letizia Taddei et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Regulation of Androgen Receptor Transcriptional Activity and Specificity by RNF6-induced Ubiquitination
Kexin Xu et al.
CANCER CELL (2009)
CXC Receptor-1 Silencing Inhibits Androgen-Independent Prostate Cancer
Nagarajarao Shamaladevi et al.
CANCER RESEARCH (2009)
Histone Deacetylases Are Required for Androgen Receptor Function in Hormone-Sensitive and Castrate-Resistant Prostate Cancer
Derek S. Welsbie et al.
CANCER RESEARCH (2009)
Role of p53 in the anti-proliferative effects of Sirt1 inhibition in prostate cancer cells
Brittney Jung-Hynes et al.
CELL CYCLE (2009)
Generation of an epigenetic signature by chronic hypoxia in prostate cells
Jenny A. Watson et al.
HUMAN MOLECULAR GENETICS (2009)
Recruitment of HDAC4 by transcription factor YY1 represses HOXB13 to affect cell growth in AR-negative prostate cancers
Guoling Ren et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2009)
Deficient histone acetylation and excessive deacetylase activity as epigenomic marks of prostate cancer cells
Shundong Cang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2009)
Role of Sirtuin Histone Deacetylase SIRT1 in Prostate Cancer A TARGET FOR PROSTATE CANCER MANAGEMENT VIA ITS INHIBITION?
Brittney Jung-Hynes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Core3 O-Glycan Synthase Suppresses Tumor Formation and Metastasis of Prostate Carcinoma PC3 and LNCaP Cells through Down-regulation of α2β1 Integrin Complex
Seung Ho Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Inhibition of fatty acid synthase by luteolin post-transcriptionally down-regulates c-Met expression independent of proteosomal/lysosomal degradation
David T. Coleman et al.
MOLECULAR CANCER THERAPEUTICS (2009)
HDAC6 Regulates Androgen Receptor Hypersensitivity and Nuclear Localization via Modulating Hsp90 Acetylation in Castration-Resistant Prostate Cancer
Junkui Ai et al.
MOLECULAR ENDOCRINOLOGY (2009)
SUMO-Specific Protease 1 (SENP1) Reverses the Hormone-Augmented SUMOylation of Androgen Receptor and Modulates Gene Responses in Prostate Cancer Cells
Sanna Kaikkonen et al.
MOLECULAR ENDOCRINOLOGY (2009)
p63 Promotes Cell Survival through Fatty Acid Synthase (Publication with Expression of Concern. See vol. 14, 2019)
Venkata Sabbisetti et al.
PLOS ONE (2009)
Interleukin-4 Activates Androgen Receptor Through CBP/p300
Soo Ok Lee et al.
PROSTATE (2009)
Modification-specific proteomics: Strategies for characterization of post-translational modifications using enrichment techniques
Yingming Zhao et al.
PROTEOMICS (2009)
Akt finds its new path to regulate cell cycle through modulating Skp2 activity and its destruction by APC/Cdh1
Daming Gao et al.
CELL DIVISION (2009)
A role for SIRT1 in cell growth and chemoresistance in prostate cancer PC3 and DU145 cells
Keitaro Kojima et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Statin induces apoptosis and cell growth arrest in prostate cancer cells
Ashraful Hoque et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2008)
WW domain-containing E3 ubiquitin protein ligase 1 targets p63 transcription factor for ubiquitin-mediated proteasomal degradation and regulates apoptosis
Y. Li et al.
CELL DEATH AND DIFFERENTIATION (2008)
Role of epithelial cell fibroblast growth factor receptor substrate 2α in prostate development, regeneration and tumorigenesis
Yongyou Zhang et al.
DEVELOPMENT (2008)
A Feedback Loop between the Androgen Receptor and a NEDD4-binding Protein, PMEPA1, in Prostate Cancer Cells
Hongyun Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Focal Adhesion Kinase Controls Aggressive Phenotype of Androgen-Independent Prostate Cancer
Thomas R. Johnson et al.
MOLECULAR CANCER RESEARCH (2008)
CXCL12/CXCR4 transactivates HER2 in lipid rafts of prostate cancer cells and promotes growth of metastatic deposits in bone
Sreenivasa R. Chinni et al.
MOLECULAR CANCER RESEARCH (2008)
The WW domain containing E3 ubiquitin protein ligase 1 upregulates ErbB2 and EGFR through RING finger protein 11
C. Chen et al.
ONCOGENE (2008)
Genomic Androgen Receptor-Occupied Regions with Different Functions, Defined by Histone Acetylation, Coregulators and Transcriptional Capacity
Li Jia et al.
PLOS ONE (2008)
Altered fibroblast growth factor receptor 4 stability promotes prostate cancer progression
Jianghua Wang et al.
NEOPLASIA (2008)
Ubiquitination by TOPORS regulates the prostate tumor suppressor NKX3.1
Bin Guan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Ubiquitylation of epsilon-COP by PIRH2 and regulation of the secretion of PSA
Satoru Maruyama et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2008)
SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells
Jung Hwa Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers
Liyong Zhang et al.
NATURE MEDICINE (2007)
Sirtuin 1 is required for antagonist-induced transcriptional repression of androgen-responsive genes by the androgen receptor
Yan Dai et al.
MOLECULAR ENDOCRINOLOGY (2007)
O-glycosylation regulates LNCaP prostate cancer cell susceptibility to apoptosis induced by galectin-1
Hector F. Valenzuela et al.
CANCER RESEARCH (2007)
Cholesterol sensitivity of endogenous and myristoylated Akt
Rosalyn M. Adam et al.
CANCER RESEARCH (2007)
Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate cancer
C. Chen et al.
ONCOGENE (2007)
Insulin-like growth factor 1/insulin signaling activates androgen signaling through direct interactions of Foxo1 with androgen receptor
WuQiang Fan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Site-specific acetylation of p53 directs selective transcription complex assembly
Somdutta Roy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Hormonal control of androgen receptor function through SIRT1
Maofu Fu et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Human PIRH2 enhances androgen receptor signaling through inhibition of histone deacetylase 1 and is overexpressed in prostate cancer
Ian R. Logan et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Role of desumoylation in the development of prostate cancer
Jinke Cheng et al.
NEOPLASIA (2006)
Gli2 is targeted for ubiquitination and degradation by β-TrCP ubiquitin ligase
Neehar Bhatia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Insulin-like growth factor I secreted from prostate stromal cells mediates tumor-stromal cell interactions of prostate cancer
M Kawada et al.
CANCER RESEARCH (2006)
SUMO-3 enhances androgen receptor transcriptional activity through a sumoylation-independent mechanism in prostate cancer cells
Z Zheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: The role of bone microenvironment-associated CXCL12
SR Chinni et al.
PROSTATE (2006)
Human Kruppel-like factor 5 is a target of the E3 ubiquitin ligase WWP1 for proteolysis in epithelial cells
CS Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Stabilization of E2F1 protein by MDM2 through the E2F1 ubiquitination pathway
Z Zhang et al.
ONCOGENE (2005)
Regulation of Kruppel-like factor 6 tumor suppressor activity by acetylation
D Li et al.
CANCER RESEARCH (2005)
Expression of core 2 β1,6-N-acetylglucosaminyltransferase facilitates prostate cancer progression
S Hagisawa et al.
GLYCOBIOLOGY (2005)
Global histone modification patterns predict risk of prostate cancer recurrence
DB Seligson et al.
NATURE (2005)
HIF-1α, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complexthat regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas
MJ Gray et al.
ONCOGENE (2005)
Transcriptional regulation of a metastasis suppressor gene by Tip60 and β-catenin complexes
JH Kim et al.
NATURE (2005)
Suppression of FOXO1 activity by FHL2 through SIRT1-mediated deacetylation
YH Yang et al.
EMBO JOURNAL (2005)
Stat3 dimerization regulated by reversible acetylation of a single lysine residue
ZL Yuan et al.
SCIENCE (2005)
Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation
L Gaughan et al.
NUCLEIC ACIDS RESEARCH (2005)
Cytoplasmic sequestration of HDAC7 from mitochondrial and nuclear compartments upon initiation of apoptosis
RE Bakin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The palmitoylation of metastasis suppressor KAI1/CD82 is important for its motility- and invasiveness-inhibitory activity
B Zhou et al.
CANCER RESEARCH (2004)
Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth
MF Fu et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Expression of Tip60, an androgen receptor coactivator, and its role in prostate cancer development
K Halkidou et al.
ONCOGENE (2003)
Cytoscape: A software environment for integrated models of biomolecular interaction networks
P Shannon et al.
GENOME RESEARCH (2003)
PIAS1 and PIASxα function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription
T Nishida et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Phosphorylation-dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase
HK Lin et al.
EMBO JOURNAL (2002)
Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor.
L Gaughan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Alterations in the focal adhesion kinase/Src signal transduction pathway correlate with increased migratory capacity of prostate carcinoma cells
JK Slack et al.
ONCOGENE (2001)
p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation
MF Fu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
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