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Heteromeric channels formed by TRPC1, TRPC4 and TRPC5 define hippocampal synaptic transmission and working memory
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TRPM2, a Susceptibility Gene for Bipolar Disorder, Regulates Glycogen Synthase Kinase-3 Activity in the Brain
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JOURNAL OF NEUROSCIENCE (2015)
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Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice
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PLOS ONE (2015)
ADP-ribose/TRPM2-mediated Ca2+ signaling is essential for cytolytic degranulation and antitumor activity of natural killer cells
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Comprehensive behavioral analysis of voltage-gated calcium channel beta-anchoring and -regulatory protein knockout mice
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Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons
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TRPM2 mediates the lysophosphatidic acid-induced neurite retraction in the developing brain
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Neutrophil TRPM2 channels are implicated in the exacerbation of myocardial ischaemia/reperfusion injury
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Activation of TRPC4β by Gαi subunit increases Ca2+ selectivity and controls neurite morphogenesis in cultured hippocampal neuron
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TRPM2 Channels Are Required for NMDA-Induced Burst Firing and Contribute to H2O2-Dependent Modulation in Substantia Nigra Pars Reticulata GABAergic Neurons
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TRPA1 Channels Are Regulators of Astrocyte Basal Calcium Levels and Long-Term Potentiation via Constitutive D-Serine Release
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A TRPC1-mediated increase in store-operated Ca2+ entry is required for the proliferation of adult hippocampal neural progenitor cells
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TRPC5 Channel Is the Mediator of Neurotrophin-3 in Regulating Dendritic Growth via CaMKIIα in Rat Hippocampal Neurons
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Forebrain elimination of cacna1c mediates anxiety-like behavior in mice
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The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation
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TRPA1 channels regulate astrocyte resting calcium and inhibitory synapse efficacy through GAT-3
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Calpain cleaves and activates the TRPC5 channel to participate in semaphorin 3A-induced neuronal growth cone collapse
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Redox signal-mediated sensitization of transient receptor potential melastatin 2 (TRPM2) to temperature affects macrophage functions
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Lack of TRPM2 Impaired Insulin Secretion and Glucose Metabolisms in Mice
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Allyl isothiocyanates and cinnamaldehyde potentiate miniature excitatory postsynaptic inputs in the supraoptic nucleus in rats
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EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
A TRPC5-regulated calcium signaling pathway controls dendrite patterning in the mammalian brain
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The Cannabinoid WIN 55,212-2-Mediated Protection of Dentate Gyrus Granule Cells is Driven by CB1 Receptors and Modulated by TRPA1 and Cav2.2 Channels
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HIPPOCAMPUS (2011)
Cholecystokinin facilitates neuronal excitability in the entorhinal cortex via activation of TRPC-like channels
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TRPA1 underlies a sensing mechanism for O2
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Genome-wide association study identifies five new schizophrenia loci
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Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes
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Dependence of NMDA/GSK-3β Mediated Metaplasticity on TRPM2 Channels at Hippocampal CA3-CA1 Synapses
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Genetic Variation in CACNA1C Affects Brain Circuitries Related to Mental Illness
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Observational fear learning involves affective pain system and Cav1.2 Ca2+ channels in ACC
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TRPC Channels Mediate a Muscarinic Receptor-Induced Afterdepolarization in Cerebral Cortex
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Ca2+-dependent induction of TRPM2 currents in hippocampal neurons
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Peptidyl-Prolyl Isomerase FKBP52 Controls Chemotropic Guidance of Neuronal Growth Cones via Regulation of TRPC1 Channel Opening
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Transient receptor potential A1 increase glutamate release on brain stem neurons
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TRPC channel activation by extracellular thioredoxin
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TRPM2-mediated Ca2+ influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
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TRPV1 channels mediate long-term depression at synapses on hippocampal interneurons
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Altered antioxidant defense system in clinidcally stable patients with schizophrenia and their unaffected siblings
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Multiple cascade effects of oxidative stress on astroglia
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Major depressive disorder is accompanied with oxidative stress: short-term antidepressant treatment does not alter oxidative-antioxidative systems
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Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
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TRP channel activation by reversible covalent modification
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Nitric oxide activates TRP channels by cysteine S-nitrosylation
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TRPA1 is a substrate for de-ubiquitination by the tumor suppressor CYLD
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TRPM2 activation by cyclic ADP-ribose at body temperature is involved in insulin secretion
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Tissue distribution profiles of the human TRPM cation channel family
E Fonfria et al.
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Fine mapping of a susceptibility locus for bipolar and genetically related unipolar affective disorders, to a region containing the C21ORF29 and TRPM2 genes on chromosome 21q22.3
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MOLECULAR PSYCHIATRY (2006)
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Supplementation of vitamin C with atypical antipsychotics reduces oxidative stress and improves the outcome of schizophrenia
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Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory
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JOURNAL OF NEUROSCIENCE (2005)
Sensing with TRP channels
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NATURE CHEMICAL BIOLOGY (2005)
Visualization of localized store-operated calcium entry in mouse astrocytes. Close proximity to the endoplasmic reticulum
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Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor
Y Li et al.
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Requirement of TRPC channels in netrin-1-induced chemotropic turning of nerve growth cones
GX Wang et al.
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Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels
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JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Canonical transient receptor potential channel 4 (TRPC4) co-localizes with the scaffolding protein ZO-1 in human fetal astrocytes in culture
XY Song et al.
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Effects of the vanilloid agonist olvanil and antagonist capsazepine on rat behaviors
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[3H]resiniferatoxin autoradiography in the CNS of wild-type and TRPV1 null mice defines TRPV1 (VR-1) protein distribution
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Antioxidant enzyme and malondialdehyde values in social phobia before and after citalopram treatment
M Atmaca et al.
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Hydrogen peroxide and ADP-ribose induce TRPM2-mediated calcium influx and cation currents in microglia
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Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus
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Evidence that the activities of erythrocyte free radical scavenging enzymes and the products of lipid peroxidation ape increased in different forms of schizophrenia
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