期刊
FRONTIERS IN ONCOLOGY
卷 10, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fonc.2020.617868
关键词
choroidal melanoma; multimodal imaging; diagnosis; staging; positron-emission tomography; computed tomography scan
类别
资金
- Natural Science Foundation of China [82070954]
- Applied Basic Research Programs of Science and Technology Commission Foundation of Sichuan Province [19YYJC0790]
- Innovative Spark Grant of Sichuan University [2018SCUH0062]
Choroidal melanomas are the most common ocular malignant tumors worldwide, requiring early diagnosis. The onset of these tumors is insidious, necessitating enucleation; they easily metastasize to the liver, leading to patient mortality. Molecular imaging plays a crucial role in early diagnosis.
Choroidal melanomas are the most common ocular malignant tumors worldwide. The onset of such tumors is insidious, such that affected patients often have no pain or obvious discomfort during early stages. Notably, enucleation is required for patients with a severe choroidal melanoma, which can seriously impact their quality of life. Moreover, choroidal melanomas metastasize early, often to the liver; this eventually causes affected patients to die of liver failure. Therefore, early diagnosis of choroidal melanomas is extremely important. Unfortunately, an early choroidal melanoma is easily confused with a choroidal nevus, which is the most common benign tumor of the eye and does not often require surgical treatment. This review discusses recent advances in the use of multimodal and molecular imaging to identify choroidal melanomas and choroidal nevi, detect early metastasis, and diagnose patients with choroidal melanomas.
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