A Review of Newly Diagnosed Glioblastoma

Glioblastoma is an aggressive and inevitably recurrent primary intra-axial brain tumor with a dismal prognosis. The current mainstay of treatment involves maximally safe surgical resection followed by radiotherapy over a 6-week period with concomitant temozolomide chemotherapy followed by temozolomide maintenance. This review provides a summary of the epidemiological, clinical, histologic and genetic characteristics of newly diagnosed disease as well as the current standard of care and potential future therapeutic prospects.

Automated summary

Glioblastoma is an aggressive primary intra-axial brain tumor with poor prognosis, and current treatment involves surgery, radiotherapy, and chemotherapy. This review summarizes the characteristics, current treatment options, and potential future therapeutic prospects for the disease.