4.6 Editorial Material

Molecular and Cellular Basis of Autoimmune Diseases

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Cell Biology

Herpesvirus Antibodies, Vitamin D and Short-Chain Fatty Acids: Their Correlation with Cell Subsets in Multiple Sclerosis Patients and Healthy Controls

Maria Inmaculada Dominguez-Mozo et al.

Summary: This study analyzed the humoral response to certain viruses, levels of 25-hydroxyvitamin D, and short-chain fatty acids in MS patients and healthy controls, finding significant differences in environmental factors between the two groups. The strongest correlations were found with 25(OH)D and SCFAs levels, suggesting potential implications in the pathogenesis of the disease. In untreated MS patients, the interaction between vitamin D levels and SCFA ratio negatively correlated with certain T cell subsets, indicating a possible avenue for future therapies.
Review Cell Biology

Adipokines and Autoimmunity in Inflammatory Arthritis

Elena Neumann et al.

Summary: Adipokines are factors derived from adipose tissue that play a crucial role in metabolism and influence inflammation and other central processes in the body. In autoimmune diseases, adipokines are involved in inflammatory pathways that affect different cell types, contributing to conditions like rheumatoid arthritis. Changes in systemic adipokine levels suggest their potential as biomarkers for rheumatic diseases, particularly in the context of inflammatory arthritis like rheumatoid arthritis.
Review Cell Biology

Complement as a Therapeutic Target in Systemic Autoimmune Diseases

Maria Galindo-Izquierdo et al.

Summary: The complement system, consisting of more than 50 proteins, plays a key role in recognizing and protecting against foreign or damaged molecular components. Pathological activation of the complement system is involved in the pathogenesis of autoimmune diseases, and it may serve as a potential therapeutic target in rheumatologic autoimmune processes.
Article Cell Biology

Prolactin Rescues Immature B Cells from Apoptosis-Induced BCR-Aggregation through STAT3, Bcl2a1a, Bcl2l2, and Birc5 in Lupus-Prone MRL/lpr Mice

Rocio Flores-Fernandez et al.

Summary: Immature B cells in lupus-prone mice can be rescued from apoptosis by prolactin signaling pathway and play a crucial role in the development of lupus. Prolactin rescues self-reactive immature B cells by activating STAT3 and regulating transcription of genes related to apoptosis resistance.
Review Biochemistry & Molecular Biology

A Clinical Approach for the Use of VIP Axis in Inflammatory and Autoimmune Diseases

Carmen Martinez et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Cell Biology

Identification of Novel Molecular Markers of Human Th17 Cells

Anna Salkowska et al.

Review Cell Biology

The Multi-Omics Architecture of Juvenile Idiopathic Arthritis

Xiaoyuan Hou et al.

Review Endocrinology & Metabolism

An Overview of VPAC Receptors in Rheumatoid Arthritis: Biological Role and Clinical Significance

Rosa P. Gomariz et al.

FRONTIERS IN ENDOCRINOLOGY (2019)

Review Immunology

The immunopathogenesis of seropositive rheumatoid arthritis: from triggering to targeting

Vivianne Malmstrom et al.

NATURE REVIEWS IMMUNOLOGY (2017)

Review Urology & Nephrology

Complement in disease: a defence system turning offensive

Daniel Ricklin et al.

NATURE REVIEWS NEPHROLOGY (2016)

Review Cell Biology

The biological functions of miRNAs: lessons from in vivo studies

Joana A. Vidigal et al.

TRENDS IN CELL BIOLOGY (2015)

Article Genetics & Heredity

The pathogenic Th profile of human activated memory Th cells in early rheumatoid arthritis can be modulated by VIP

Rebeca Jimeno et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2015)

Article Pharmacology & Pharmacy

Biomarkers Predicting a Need for Intensive Treatment in Patients with Early Arthritis

I. Gonzalez-Alvaro et al.

CURRENT PHARMACEUTICAL DESIGN (2014)

Article Medicine, General & Internal

Systemic lupus erythematosus

Larissa Lisnevskaia et al.

LANCET (2014)

Review Immunology

T helper 17 cell heterogeneity and pathogenicity in autoimmune disease

Kamran Ghoreschi et al.

TRENDS IN IMMUNOLOGY (2011)

Article Multidisciplinary Sciences

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

Kiran Nistala et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)