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Delta Np63 alpha mediates proliferation and apoptosis in human gastric cancer cells by the regulation of GATA-6
H. Wang et al.
NEOPLASMA (2012)
Histone demethylase JMJD2B is required for tumor cell proliferation and survival and is overexpressed in gastric cancer
Wenjuan Li et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan
Xin Liu et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)
Coleusin factor exerts cytotoxic activity by inducing G0/G1 cell cycle arrest and apoptosis in human gastric cancer BGC-823 cells
Bo Sun et al.
CANCER LETTERS (2011)
p53 Negatively Regulates the Hepatoma Growth Factor HDGF
Yasushi Sasaki et al.
CANCER RESEARCH (2011)
Potent in vitro and in vivo antitumor effects of MDM2 inhibitor nutlin-3 in gastric cancer cells
Shinji Endo et al.
CANCER SCIENCE (2011)
Gastric cancer in individuals with Li-Fraumeni syndrome
Serena Masciari et al.
GENETICS IN MEDICINE (2011)
Helicobacter pylori affects the cellular deubiquitinase USP7 and ubiquitin-regulated components TRAF6 and the tumour suppressor p53
Nina Coombs et al.
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY (2011)
Complex Regulation of p73 Isoforms after Alteration of Amyloid Precursor Polypeptide (APP) Function and DNA Damage in Neurons
Samir Benosman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
H2S Donor, S-Propargyl-Cysteine, Increases CSE in SGC-7901 and Cancer-Induced Mice: Evidence for a Novel Anti-Cancer Effect of Endogenous H2S?
Kaium Ma et al.
PLOS ONE (2011)
Changes in the gene expression profile of gastric cancer cells in response to ibuprofen: a gene pathway analysis
P. Bonelli et al.
PHARMACOGENOMICS JOURNAL (2011)
Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the host
Ludovico Buti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
rAd-p53 enhances the sensitivity of human gastric cancer cells to chemotherapy
Guang-Xia Chen et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2011)
Blocking NF-κB nuclear translocation leads to p53-related autophagy activation and cell apoptosis
Bao-Song Zhu et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2011)
Reciprocal influence of the p53 and the hypoxic pathways
A. Sermeus et al.
CELL DEATH & DISEASE (2011)
Overexpression of p73 as a Tissue Marker for High-Risk Gastritis
Gonzalo Carrasco et al.
CLINICAL CANCER RESEARCH (2010)
Regulation of p53 Tumor Suppressor by Helicobacter pylori in Gastric Epithelial Cells
Jinxiong Wei et al.
GASTROENTEROLOGY (2010)
Identification of a functional p53 responsive element within the promoter of XAF1 gene in gastrointestinal cancer cells
Wenjing Zhang et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2010)
Enigma negatively regulates p53 through MDM2 and promotes tumor cell survival in mice
Cho-Rok Jung et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Inhibition of the p53-MDM2 interaction by adenovirus delivery of ribosomal protein L23 stabilizes p53 and induces cell cycle arrest and apoptosis in gastric cancer
Yafei Zhang et al.
JOURNAL OF GENE MEDICINE (2010)
Characterization of ΔNp73 expression and regulation in gastric and esophageal tumors
A. E. Vilgelm et al.
ONCOGENE (2010)
Hypoxia-Inducible Factor 1α Determines Gastric Cancer Chemosensitivity via Modulation of p53 and NF-κB
Nadine Rohwer et al.
PLOS ONE (2010)
p53 Research: The Past Thirty Years and the Next Thirty Years
David Lane et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2010)
p53 inhibition of AP1-dependent TFF2 expression induces apoptosis and inhibits cell migration in gastric cancer cells
Shui Ping Tu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)
Frequent promoter hypermethylation and transcriptional downregulation of BTG4 gene in gastric cancer
Wenjie Dong et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
Identification of retinoic acid-regulated nuclear matrix-associated protein as a novel regulator of gastric cancer
J. Li et al.
BRITISH JOURNAL OF CANCER (2009)
TP53 codon 72 polymorphism associated with prognosis in patients with advanced gastric cancer treated with paclitaxel and cisplatin
Jong Gwang Kim et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2009)
Polymorphisms in p53, GSTP1 and XRCC1 predict relapse and survival of gastric cancer patients treated with oxaliplatin-based adjuvant chemotherapy
Zhao-Hui Huang et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2009)
Arsenic trioxide induces apoptosis and G2/M phase arrest by inducing Cbl to inhibit PI3K/Akt signaling and thereby regulate p53 activation
Yingchun Li et al.
CANCER LETTERS (2009)
p53-Altered FBXW7 Expression Determines Poor Prognosis in Gastric Cancer Cases
Takehiko Yokobori et al.
CANCER RESEARCH (2009)
DNA methyltransferase inhibitor 5-aza-CdR enhances the radiosensitivity of gastric cancer cells
Hong Qiu et al.
CANCER SCIENCE (2009)
Reduction of TIP30 correlates with poor prognosis of gastric cancer patients and its restoration drastically inhibits tumor growth and metastasis
Xiaohua Li et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
A case-control study on the effect of p53 and p73 gene polymorphisms on gastric cancer risk and progression
Emma De Feo et al.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS (2009)
Epstein-Barr virus nuclear antigen 3C targets p53 and modulates its transcriptional and apoptotic activities
Fuming Yi et al.
VIROLOGY (2009)
Degradation of Phosphorylated p53 by Viral Protein-ECS E3 Ligase Complex
Yoshitaka Sato et al.
PLOS PATHOGENS (2009)
Class I phosphatidylinositol 3-kinase inhibitor LY294002 activates autophagy and induces apoptosis through p53 pathway in gastric cancer cell line SGC7901
Chungen Xing et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2008)
IRF-2 regulates NF-κB activity by modulating the subcellular localization of NF-κB
Myounghee Chae et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Role of TAp73α in induction of apoptosis by transforming growth factor-β in gastric cancer cells
Yasuko Yamamura et al.
FEBS LETTERS (2008)
Interaction of helicobacter pylori with gastric epithelial cells is mediated by the p53 protein family
Anxiong Wei et al.
GASTROENTEROLOGY (2008)
Histone deacetylase inhibitor FK228 enhances adenovirus-mediated p53 family gene therapy in cancer models
Yasushi Sasaki et al.
MOLECULAR CANCER THERAPEUTICS (2008)
ΔNp73α regulates MDR1 expression by inhibiting p53 function
A. Vilgelm et al.
ONCOGENE (2008)
Frequent epigenetic inactivation of hSRBC in gastric cancer and its implication in attenuated p53 response to stresses
Jin-Hee Lee et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
P53 codon 72 polymorphism and gastric cancer: A meta-analysis of the literature
Yong Zhou et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
Shaping genetic alterations in human cancer: The p53 mutation paradigm
Thierry Soussi et al.
CANCER CELL (2007)
Involvement of up-regulation of PUMA in non-steroidal anti-inflammatory drug-induced apoptosis
Tomoaki Ishihara et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
Yuko Matsumoto et al.
NATURE MEDICINE (2007)
Immunostaining of thymidylate synthase and p53 for predicting chemoresistance to S-1/cisplatin in gastric cancer
S. Kamoshida et al.
BRITISH JOURNAL OF CANCER (2007)
Suppression of gastric cancer cell growth by targeting the β-catenin/T-cell factor pathway
Hadas Dvory-Sobol et al.
CANCER (2007)
p53 family isoforms
Jean-Christophe Bourdon
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2007)
p73 gene promoter methylation in Epstein-Barr virus-associated gastric carcinoma
Tetsuo Ushiku et al.
INTERNATIONAL JOURNAL OF CANCER (2007)
MDM2 promoter polymorphism is associated with both an increased susceptibility to gastric carcinoma and poor prognosis
Naoki Ohmiya et al.
JOURNAL OF CLINICAL ONCOLOGY (2006)
Overexpression of hypoxia-inducible factor 1α and p53 is a marker for an unfavorable prognosis in gastric cancer
Yasushi Sumiyoshi et al.
CLINICAL CANCER RESEARCH (2006)
p51/p63, a novel p53 homologue, potentiates p53 activity and is a human cancer gene therapy candidate
Reiko Kunisaki et al.
JOURNAL OF GENE MEDICINE (2006)
Oncogenic T-antigen of JC virus is present frequently in human gastric cancers
Sung Kwan Shin et al.
CANCER (2006)
Role of Rac1 and Cdc42 in hypoxia induced p53 and von Hippel-Lindau suppression and HIF1α activation
Yan Xue et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
p53 transgenic mice are highly susceptible to 4-nitroquinoline-1-oxide-induced oral cancer
Zhongqiu Zhang et al.
MOLECULAR CANCER RESEARCH (2006)
Mutation of Lkb1 and p53 genes exert a cooperative effect on tumorigenesis
CJ Wei et al.
CANCER RESEARCH (2005)
Combined small-cell carcinoma of the stomach: p53 and K-ras gene mutational analysis supports a monoclonal origin of three histological components
B Han et al.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY (2005)
Downregulation of XIAP expression induces apoptosis and enhances chemotherapeutic sensitivity in human gastric cancer cells
QS Tong et al.
CANCER GENE THERAPY (2005)
Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1: Implications for EBV-mediated immortalization
V Saridakis et al.
MOLECULAR CELL (2005)
Cell death induced by Pteris semipinnata L. is associated with p53 and oxidant stress in gastric cancer cells
ZM Liu et al.
FEBS LETTERS (2005)
Combined evaluation of expressions of cyclin E and p53 proteins as prognostic factors for patients with gastric cancer
KE Bani-Hani et al.
CLINICAL CANCER RESEARCH (2005)
Molecular therapy for peritoneal dissemination of xenotransplanted human MKN-45 gastric cancer cells with adenovirus mediated Bax gene transfer
Y Tsunemitsu et al.
GUT (2004)
Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP2E1, GSTM1, and NAT2), drinking habits, histological subtypes, and p53 gene point mutations in Japanese patients with gastric cancer
S Suzuki et al.
JOURNAL OF GASTROENTEROLOGY (2004)
ΔNp73 stabilises TAp73 proteins but compromises their function due to inhibitory hetero-oligomer formation
N Slade et al.
CELL DEATH AND DIFFERENTIATION (2004)
Effect of peroxisome proliferator activated receptor γ ligands on growth and gene expression profiles of gastric cancer cells
WK Leung et al.
GUT (2004)
Upregulation of heme oxygenase-1 and p21 confers resistance to apoptosis in human gastric cancer cells
ZM Liu et al.
ONCOGENE (2004)
p73 isoforms can induce T-cell factor-dependent transcription in gastrointestinal cells
K Tomkova et al.
CANCER RESEARCH (2004)
TP53 in gastric cancer: Mutations in the L3 loop and LSH motif DNA-binding domains of TP53 predict poor outcome
M Migliavacca et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2004)
Enhanced TGFα-EGFR expression and P53 gene alterations contributes to gastric tumors aggressiveness
LA Espinoza et al.
CANCER LETTERS (2004)
Synergistic tumor suppression by coexpression of FHIT and p53 coincides with FHIT-mediated MDM2 inactivation and p53 stabilization in human non-small cell lung cancer cells
M Nishizaki et al.
CANCER RESEARCH (2004)
E-Cadherin (CDH1) and p53 rather than SMAD4 and Caspase-10 germline mutations contribute to genetic predisposition in Portuguese gastric cancer patients
C Oliveira et al.
EUROPEAN JOURNAL OF CANCER (2004)
p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2
M Urist et al.
GENES & DEVELOPMENT (2004)
p53 polymorphism and p21WAF1/CIP1 haplotype in the intestinal gastric cancer and the precancerous lesions
YG Xi et al.
CARCINOGENESIS (2004)
Prognostic value of TP53 codon 72 polymorphism in advanced gastric adenocarcinoma
ZW Zhang et al.
CLINICAL CANCER RESEARCH (2004)
p53 and VEGF expression are independent predictors of tumour recurrence and survival following curative resection of gastric cancer
C Fondevila et al.
BRITISH JOURNAL OF CANCER (2004)
Development of gastric carcinoma from intestinal metaplasia in CDx2-transgenic mice
H Mutoh et al.
CANCER RESEARCH (2004)
A TP53-truncating germline mutation (E287X) in a family with characteristics of both hereditary diffuse gastric cancer and Li-Fraumeni syndrome
IJ Kim et al.
JOURNAL OF HUMAN GENETICS (2004)
Dependence of chemotherapy response on p53 mutation status in a panel of human cancer lines maintained in nude mice
M Koike et al.
CANCER SCIENCE (2004)
CP-31398, a novel p53-stabilizing agent, induces p53-dependent and p53-independent glioma cell death
J Wischhusen et al.
ONCOGENE (2003)
Induction of apoptosis and expression of apoptosis related genes in human epithelial carcinoma cells by Helicobacter pylori VacA toxin
SJ Cho et al.
TOXICON (2003)
Detection of p53 mutations in precancerous gastric tissue
C Morgan et al.
BRITISH JOURNAL OF CANCER (2003)
Differential regulation of E2F1 apoptotic target genes in response to DNA damage
N Pediconi et al.
NATURE CELL BIOLOGY (2003)
PPARγ ligand-induced apoptosis through a p53-dependent mechanism in human gastric cancer cells
M Nagamine et al.
CANCER SCIENCE (2003)
Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability
A Mrózek et al.
CELL DEATH AND DIFFERENTIATION (2003)
p73 gene mutations in gastric adenocarcinomas
E Pilozzi et al.
JOURNAL OF CLINICAL PATHOLOGY-MOLECULAR PATHOLOGY (2003)
Significance of apoptosis induced by tumor necrosis factor-alpha and/or interferon-gamma against human gastric cancer cell lines and the role of the p53 gene
T Fukui et al.
SURGERY TODAY (2003)
Preferential loss of Fhit expression in signet-ring cell and Krukenberg subtypes of gastric cancer
YT Chang et al.
LABORATORY INVESTIGATION (2002)
No associations of p73 G4C14-to-A4T14 at exon 2 and p53 Arg72Pro polymorphisms with the risk of digestive tract cancers in Japanese
N Hamajima et al.
CANCER LETTERS (2002)
Analysis of p53 mutations and Helicobacter pylori infection in human and animal models
K Murakami et al.
JOURNAL OF GASTROENTEROLOGY (2002)
Gene-specific oxidative DNA damage in Helicobacter pylori -: Infected human gastric mucosa
J Choi et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
Increased expression of Chk2 in human gastric carcinomas harboring p53 mutations
H Shigeishi et al.
INTERNATIONAL JOURNAL OF CANCER (2002)
Transcriptional repression of the anti-apoptotic survivin gene by wild type p53
WH Hoffman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
CagA status of Helicobacter pylori infection and p53 gene mutations in gastric adenocarcinoma
A Shibata et al.
CARCINOGENESIS (2002)
Serrated neoplasia of the stomach: a new entity
CA Rubio
JOURNAL OF CLINICAL PATHOLOGY (2001)
Inactivating mutations of KILLER/DR5 gene in gastric cancers
WS Park et al.
GASTROENTEROLOGY (2001)
Expression of p53-related protein p63 in the gastrointestinal tract and in esophageal metaplastic and neoplastic disorders
JN Glickman et al.
HUMAN PATHOLOGY (2001)
Expression of p21WAF1/CIP1 and p53 proteins in gastric carcinoma:: its relationships with cell proliferation activity and prognosis
XP Liu et al.
CANCER LETTERS (2001)
Expression of the p53 homologues p63 and p73 in multiple simultaneous gastric cancer
A Tannapfel et al.
JOURNAL OF PATHOLOGY (2001)
Expression of p53 protein as a prognostic indicator of reduced survival time in diffuse-type gastric carcinoma
XP Liu et al.
PATHOLOGY INTERNATIONAL (2001)
A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain
C Gaiddon et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Association between cyclo-oxygenase-2 overexpression and missense p53 mutations in gastric cancer
WK Leung et al.
BRITISH JOURNAL OF CANCER (2001)
p53 knockout mice (-/-) are more susceptible than (+/-) or (+/+) mice to N-methyl-N-nitrosourea stomach carcinogenesis
M Yamamoto et al.
CARCINOGENESIS (2000)
Gastric cancer:: which patients benefit from systematic lymphadenectomy?
NM Bösing et al.
EUROPEAN JOURNAL OF SURGICAL ONCOLOGY (2000)
Expression of the p53 tumor suppressor gene is up-regulated by depletion of intracellular zinc in HepG2 cells
SK Reaves et al.
JOURNAL OF NUTRITION (2000)
Alterations in exon 4 of the p53 gene in gastric carcinoma
T Shepherd et al.
GASTROENTEROLOGY (2000)
Mdm2 gene amplification in gastric cancer correlation with expression of mdm2 protein and p53 alterations
T Günther et al.
MODERN PATHOLOGY (2000)
p21 expression is a prognostic factor in patients with p53-negative gastric cancer
XM Che et al.
CANCER LETTERS (2000)
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