期刊
JOURNAL OF CLINICAL MEDICINE
卷 10, 期 4, 页码 -出版社
MDPI
DOI: 10.3390/jcm10040729
关键词
age; atrial fibrillation; risk stratification; stroke
资金
- European Research Council (ERC) under the European Union [648131]
- European Union [847770]
- German Center for Cardiovascular Research (DZHK e.V.) [81Z1710103]
- German Ministry of Research and Education [BMBF 01ZX1408A]
- ERACoSysMed3 [031L0239]
The study aimed to assess the prevalence of unknown atrial fibrillation (AF) among adults during single-time point rhythm screening. Results showed a higher prevalence of unknown AF in the age group of >= 65 years, while no positive cases were found in the group aged below 50 years. Risk stratification based on certain criteria had high sensitivity and negative predictive value for AF detection.
Our aim was to assess the prevalence of unknown atrial fibrillation (AF) among adults during single-time point rhythm screening performed during meetings or social recreational activities organized by patient groups or volunteers. A total of 2814 subjects (median age 68 years) underwent AF screening by a handheld single-lead ECG device (MyDiagnostick). Overall, 56 subjects (2.0%) were diagnosed with AF, as a result of 12-lead ECG following a positive/suspected recording. Screening identified AF in 2.9% of the subjects >= 65 years. None of the 265 subjects aged below 50 years was found positive at AF screening. Risk stratification for unknown AF based on a CHA(2)DS(2)VASc > 0 in males and >1 in females (or CHA(2)DS(2)VA > 0) had a high sensitivity (98.2%) and a high negative predictive value (99.8%) for AF detection. A slightly lower sensitivity (96.4%) was achieved by using age >= 65 years as a risk stratifier. Conversely, raising the threshold at >= 75 years showed a low sensitivity. Within the subset of subjects aged >= 65 a CHA(2)DS(2)VASc > 1 in males and >2 in females, or a CHA(2)DS(2)VA > 1 had a high sensitivity (94.4%) and negative predictive value (99.3%), while age >= 75 was associated with a marked drop in sensitivity for AF detection.
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