COVID-19 into Chemical Science Perspective: Chemical Preventive Measures and Drug Development

COVID-19 facts and literature are discussed into chemical science intuition highlighting the direct role of chemistry to the ongoing global pandemic by covering structural identification of the virus, chemical preventive measures and development of drugs. We reviewed the four most promising repurposed drugs which are presently being investigated in mass clinical trials on COVID-19 infected persons and synthetic routes of these drugs with their recent advancement. Chemical preventive measures such as soap water, hand sanitizer and disinfectant are the only available options in the arsenal to fight against COVID-19, till an effective medicine or vaccine will be made available. As such the present review will focus on the mode of action of the major chemical preventives.

Automated summary

This article discusses the direct role of chemistry in the ongoing global COVID-19 pandemic, covering topics such as structural identification of the virus, drug development, and chemical preventive measures. The review focuses on the four most promising repurposed drugs currently undergoing clinical trials, as well as the synthetic routes and recent advancements of these drugs. Chemical preventive measures such as soap water, hand sanitizer, and disinfectant are currently the only available options to combat COVID-19.