Renal Involvement in COVID-19: A Review of the Literature

Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of the literature on the prevalence of kidney involvement, on the pathogenic pathways and on its management.

Automated summary

Kidney injury can be a severe complication of SARS-CoV-2, worsening the prognosis. Various pathophysiological mechanisms contribute to organ damage and impair renal function, highlighting the complexity of the virus activity and immune response. Researchers have summarized evidence on the prevalence of kidney involvement, pathogenic pathways, and management.