期刊
BRAIN AND COGNITION
卷 101, 期 -, 页码 51-56出版社
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.bandc.2015.11.002
关键词
tACS; Gamma; Working memory; Cognitive load
资金
- Cervel Neurotech
- Neuronetics Ltd.
- Bionomics
- Neuronetics
- CIHR Industry Partnered (Brainsway) operating grant
- Brainsway Inc
- Sepracor Inc
Transcranial Direct Current Stimulation (tDCS) has been widely investigated for its potential to enhance cognition, and in particular working memory, however to date standard approaches to stimulation have shown only modest effects. Alternative, more specialised, forms of current delivery may be better suited to cognitive enhancement. One such method is transcranial Alternating Current Stimulation (tACS) which delivers stimulation at a specific frequency and has been shown to entrain endogenous cortical oscillations which underlie cognitive functioning. To date there has been no comparison of the effects of tACS to those of tDCS on cognitive enhancement. In a randomised repeated-measures study design we assessed the effect of gamma (gamma)-tACS, tDCS and sham tDCS on working memory in 18 healthy participants who attended three sessions held at least 72 h apart. Pre- and post-stimulation working memory performance was assessed using the 2 and 3-back. Our findings indicated the presence of a selective improvement in performance on the 3-back task following beta-tACS compared with tDCS and sham stimulation. The current findings provide support for further and more detailed investigation of the role of y-tACS as a more specialised approach to neuromodulation. (C) 2015 Elsevier Inc. All rights reserved.
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