期刊
FRONTIERS IN PHARMACOLOGY
卷 11, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fphar.2020.518225
关键词
autophagy; rcc; inhibitor; inducers; PI3K; AKT; mTOR; AMPK; mTOR
Autophagy plays a crucial role in renal cell carcinoma, with many autophagy-related proteins serving as prognostic markers. Researchers are exploring synthetic and phytochemical drugs targeting autophagy for RCC therapy.
Autophagy is a process that degrades and recycles superfluous organelles or damaged cellular contents. It has been found to have dual functions in renal cell carcinoma (RCC). Many autophagy-related proteins are regarded as prognostic markers of RCC. Researchers have attempted to explore synthetic and phytochemical drugs for RCC therapy that target autophagy. In this review, we highlight the importance of autophagy in RCC and potential treatments related to autophagy.
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