4.7 Review

The Epigenetic Faces of ULTRAPETALA1

期刊

FRONTIERS IN PLANT SCIENCE
卷 12, 期 -, 页码 -

出版社

FRONTIERS MEDIA SA
DOI: 10.3389/fpls.2021.637244

关键词

ULTRAPETALA1; TrxG; PcG; ATX1; Molecular epigenetic switch; Arabidopsis

资金

  1. UNAM-DGAPA-PAPIIT [IN203220, IN206220, IN200920, IN211721]
  2. CONACyT [102987, 102959]

向作者/读者索取更多资源

ULT1 is a versatile plant-specific protein that can regulate transcription activation independently of ATX1. It interacts with transcription factors and PcG proteins, indicating diverse roles. ULT1 acts as an epigenetic molecular switch regulating repression and activation processes via TrxG and PcG complexes.
ULTRAPETALA1 (ULT1) is a versatile plant-exclusive protein, initially described as a trithorax group (TrxG) factor that regulates transcriptional activation and counteracts polycomb group (PcG) repressor function. As part of TrxG, ULT1 interacts with ARABIDOPSIS TRITHORAX1 (ATX1) to regulate H3K4me3 activation mark deposition. However, our recent studies indicate that ULT1 can also act independently of ATX1. Moreover, the ULT1 ability to interact with transcription factors (TFs) and PcG proteins indicates that it is a versatile protein with other roles. Therefore, in this work we revised recent information about the function of Arabidopsis ULT1 to understand the roles of ULT1 in plant development. Furthermore, we discuss the molecular mechanisms of ULT1, highlighting its epigenetic role, in which ULT1 seems to have characteristics of an epigenetic molecular switch that regulates repression and activation processes via TrxG and PcG complexes.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据