期刊
出版社
MDPI
DOI: 10.3390/ijerph18041839
关键词
COVID-19; case fatality rate; Canada; mortality; public health
资金
- National Research Foundation of Korea (NRF) - Korea government (MSIT) [2018R1C1B6001723]
- National Research Foundation of Korea [2018R1C1B6001723] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
A study in Canada showed significant variations in case fatality rate (CFR) among provinces, with Quebec having the highest adjusted CFR. The proportion of deaths among older individuals was found to be a contributing factor to higher CFR. Public health interventions targeting densely populated areas and elderly individuals could help reduce the mortality burden of the COVID-19 pandemic.
A total of 475,214 COVID-19 cases, including 13,659 deaths, had been recorded in Canada as of 15 December 2020. The daily reports of confirmed cases and deaths in Canada prior to 15 December 2020 were obtained from publicly available sources and used to examine regional variations in case fatality rate (CFR). Based on a factor of underestimation and the duration of time from symptom onset to death, the time-delay adjusted CFR for COVID-19 was estimated in the four most affected provinces (Quebec, Ontario, Alberta, and British Columbia) and nationwide. The model-based adjusted CFR was higher than the crude CFR throughout the pandemic, primarily owing to the incorporation in our estimation of the delay between case reports and deaths. The adjusted CFR in Canada was estimated to be 3.36% nationwide. At the provincial level, the adjusted CFR was the highest in Quebec (5.13%)-where the proportion of deaths among older individuals was also the highest among the four provinces-followed by Ontario (3.17%), British Columbia (1.97%), and Alberta (1.13%). Provincial-level variations in CFR were considerable, suggesting that public health interventions focused on densely populated areas and elderly individuals can ameliorate the mortality burden of the COVID-19 pandemic.
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