期刊
ENVIRONMENTAL MICROBIOLOGY
卷 18, 期 8, 页码 2754-2766出版社
WILEY-BLACKWELL
DOI: 10.1111/1462-2920.13354
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资金
- Natural Environment Research Council of the UK [NE/L006448/1, NE/H008918/1, NE/H016236/1]
- DAAD
- Warwick Chancellor's International Scholarship
- China Scholarship Council
- NERC [NE/L006448/1, NE/H008918/1, NE/H016236/1] Funding Source: UKRI
- Natural Environment Research Council [1228432, NE/H016236/1, 1094958, NE/L006448/1, NE/H008918/1] Funding Source: researchfish
The volatile organosulfur compound, dimethylsulfide (DMS), plays an important role in climate regulation and global sulfur biogeochemical cycles. Microbial oxidation of DMS to dimethylsulfoxide (DMSO) represents a major sink of DMS in surface seawater, yet the underlying molecular mechanisms and key microbial taxa involved are not known. Here, we reveal that Ruegeria pomeroyi, a model marine heterotrophic bacterium, can oxidize DMS to DMSO using trimethylamine monooxygenase (Tmm). Purified Tmm oxidizes DMS to DMSO at a 1:1 ratio. Mutagenesis of the tmm gene in R. pomeroyi completely abolished DMS oxidation and subsequent DMSO formation. Expression of Tmm and DMS oxidation in R. pomeroyi is methylamine-dependent and regulated at the post-transcriptional level. Considering that Tmm is present in approximately 20% of bacterial cells inhabiting marine surface waters, particularly the marine Roseobacter clade and the SAR11 clade, our observations contribute to a mechanistic understanding of biological DMSO production in surface seawater.
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