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The Medical Benefits of Vitamin K2 on Calcium-Related Disorders

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NUTRIENTS
卷 13, 期 2, 页码 -

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MDPI
DOI: 10.3390/nu13020691

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vitamin K-2; vitamin D; calcium; metabolism; osteoporosis; cardiovascular disease; parathyroid

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Vitamin K-2 plays a crucial role in calcium metabolism and shows potential benefits for osteoporosis, cardiovascular disease, parathyroid disorders, cerebral palsy, and sperm motility. Further research is needed to confirm the reproducibility of these positive effects and evaluate the feasibility of using vitamin K-2 as a treatment for these conditions.
Background: Due to the potentially crucial role of vitamin K-2 in calcium metabolism, a deficit can disrupt many mechanisms, resulting in an array of different issues, such as broken bones, stiff arteries and poor fertility. Although there has been existing research, the potential of vitamin K-2 as a treatment for conditions including cerebral palsy, parathyroid disease, heart disease and gastrointestinal disease is unknown. This review discusses the biochemistry of vitamin K and the metabolism of calcium, followed by an analysis of the current literature available on vitamin K-2 and its prospects. Methods: Using public libraries including PubMed and Wiley, we searched for existing research on the metabolism and use of vitamin K-2 that has been conducted in the preceding two decades. Results: Data indicated that vitamin K-2 had a positive impact on osteoporosis, cardiovascular disease, parathyroid disorders, cerebral palsy and sperm motility. Conclusion: Due to the existence of confounding variables and limitations in the quality and volume of research conducted, further investigation must be done to see whether the beneficial effects seen are reproducible and must assess the viability of vitamin K-2 as treatment in isolation for these conditions.

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