4.8 Article

A deep learning method for HLA imputation and trans-ethnic MHC fine-mapping of type 1 diabetes

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Article Multidisciplinary Sciences

A deep learning method for HLA imputation and trans-ethnic MHC fine-mapping of type 1 diabetes

Tatsuhiko Naito et al.

Summary: The study presents a deep learning method called DEEP*HLA for imputing HLA genotypes, which achieves high accuracy, especially for low-frequency and rare alleles. The results demonstrate that DEEP*HLA can successfully disentangle HLA variant risk effects in diverse populations.

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