相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Aldehyde Dehydrogenase Inhibition Ameliorates Cardiac Dysfunction and Exacerbates Hypotension Caused by Alcohol in Female Rats
Fanrong Yao et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2020)
Proteomics and Metabolomics in Kidney Disease, including Insights into Etiology, Treatment, and Prevention
Ruth F. Dubin et al.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)
Single-cell transcriptome analysis reveals differential nutrient absorption functions in human intestine
Yalong Wang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans
Pascal Schlosser et al.
NATURE GENETICS (2020)
Quantitative Proteomics of All 14 Renal Tubule Segments in Rat
Kavee Limbutara et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)
Personalized whole-body models integrate metabolism, physiology, and the gut microbiome
Ines Thiele et al.
MOLECULAR SYSTEMS BIOLOGY (2020)
Kinetic and structural analysis of human ALDH9A1
Radka Koncitikova et al.
BIOSCIENCE REPORTS (2019)
Creation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0
Laurent Heirendt et al.
NATURE PROTOCOLS (2019)
Comprehensive Integration of Single-Cell Data
Tim Stuart et al.
CELL (2019)
A human liver cell atlas reveals heterogeneity and epithelial progenitors
Nadim Aizarani et al.
NATURE (2019)
Spatiotemporal immune zonation of the human kidney
Benjamin J. Stewart et al.
SCIENCE (2019)
A Network of SLC and ABC Transporter and DME Genes Involved in Remote Sensing and Signaling in the Gut-Liver-Kidney Axis
Sara Brin Rosenthal et al.
SCIENTIFIC REPORTS (2019)
The Virtual Metabolic Human database: integrating human and gut microbiome metabolism with nutrition and disease
Alberto Noronha et al.
NUCLEIC ACIDS RESEARCH (2019)
HMDB 4.0: the human metabolome database for 2018
David S. Wishart et al.
NUCLEIC ACIDS RESEARCH (2018)
Metabolomics Research in Chronic Kidney Disease
Morgan E. Grams et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2018)
Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms
Yong Li et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2018)
Recon3D enables a three-dimensional view of gene variation in human metabolism
Elizabeth Brunk et al.
NATURE BIOTECHNOLOGY (2018)
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
Hilary K. Finucane et al.
NATURE GENETICS (2018)
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries
Mary F. Feitosa et al.
PLOS ONE (2018)
Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease
Jihwan Park et al.
SCIENCE (2018)
Genome-Wide Association Studies of Metabolite Concentrations (mGWAS): Relevance for Nephrology
Anna Koettgen et al.
SEMINARS IN NEPHROLOGY (2018)
Whole-exome sequencing identifies common and rare variant metabolic QTLs in a Middle Eastern population
Noha A. Yousri et al.
NATURE COMMUNICATIONS (2018)
Comparative Analysis and Refinement of Human PSC-Derived Kidney Organoid Differentiation with Single-Cell Transcriptomics
Haojia Wu et al.
CELL STEM CELL (2018)
The UK Biobank resource with deep phenotyping and genomic data
Clare Bycroft et al.
NATURE (2018)
Genome-wide association meta-analysis yields 20 loci associated with gallstone disease
Egil Ferkingstad et al.
NATURE COMMUNICATIONS (2018)
Urinary metabolites along with common and rare genetic variations are associated with incident chronic kidney disease
Gearoid M. McMahon et al.
KIDNEY INTERNATIONAL (2017)
Genetic effects on gene expression across human tissues
Francois Aguet et al.
NATURE (2017)
Whole-genome sequencing identifies common-to-rare variants associated with human blood metabolites
Tao Long et al.
NATURE GENETICS (2017)
Biochemical insights from population studies with genetics and metabolomics
Karsten Suhre et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2016)
dbNSFP v3.0: A One-Stop Database of Functional Predictions and Annotations for Human Nonsynonymous and Splice-Site SNVs
Xiaoming Liu et al.
HUMAN MUTATION (2016)
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine
Padhraig Gormley et al.
NATURE GENETICS (2016)
An exome array study of the plasma metabolome
Eugene P. Rhee et al.
NATURE COMMUNICATIONS (2016)
Deep Sequencing in Microdissected Renal Tubules Identifies Nephron Segment-Specific Transcriptomes
Jae Wook Lee et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2015)
Comparative Analysis of Yeast Metabolic Network Models Highlights Progress, Opportunities for Metabolic Reconstruction
Benjamin D. Heavner et al.
PLOS COMPUTATIONAL BIOLOGY (2015)
Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality
Johannes Raffler et al.
PLOS GENETICS (2015)
Disease burden and risk profile in referred patients with moderate chronic kidney disease: composition of the German Chronic Kidney Disease (GCKD) cohort
Stephanie Titze et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2015)
C7orf10 encodes succinate-hydroxymethylglutarate CoA-transferase, the enzyme that converts glutarate to glutaryl-CoA
Simon Marlaire et al.
JOURNAL OF INHERITED METABOLIC DISEASE (2014)
An atlas of genetic influences on human blood metabolites
So-Youn Shin et al.
NATURE GENETICS (2014)
Illumina human exome genotyping array clustering and quality control
Yan Guo et al.
NATURE PROTOCOLS (2014)
Predicting the impact of diet and enzymopathies on human small intestinal epithelial cells
Swagatika Sahoo et al.
HUMAN MOLECULAR GENETICS (2013)
A community-driven global reconstruction of human metabolism
Ines Thiele et al.
NATURE BIOTECHNOLOGY (2013)
HMDB 3.0-The Human Metabolome Database in 2013
David S. Wishart et al.
NUCLEIC ACIDS RESEARCH (2013)
Best Practices and Joint Calling of the HumanExome BeadChip: The CHARGE Consortium
Megan L. Grove et al.
PLOS ONE (2013)
zCall: a rare variant caller for array-based genotyping
Jacqueline I. Goldstein et al.
BIOINFORMATICS (2012)
On the hypothesis-free testing of metabolite ratios in genome-wide and metabolome-wide association studies
Ann-Kristin Petersen et al.
BMC BIOINFORMATICS (2012)
A compendium of inborn errors of metabolism mapped onto the human metabolic network
Swagatika Sahoo et al.
MOLECULAR BIOSYSTEMS (2012)
Metabolomics in the study of kidney diseases
Robert H. Weiss et al.
NATURE REVIEWS NEPHROLOGY (2012)
The German Chronic Kidney Disease (GCKD) study: design and methods
Kai-Uwe Eckardt et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2012)
Rare-Variant Association Testing for Sequencing Data with the Sequence Kernel Association Test
Michael C. Wu et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2011)
A comprehensive genome-scale reconstruction of Escherichia coli metabolism-2011
Jeffrey D. Orth et al.
MOLECULAR SYSTEMS BIOLOGY (2011)
Human metabolic individuality in biomedical and pharmaceutical research
Karsten Suhre et al.
NATURE (2011)
A genome-wide association study of metabolic traits in human urine
Karsten Suhre et al.
NATURE GENETICS (2011)
Molecular Identification of NAT8 as the Enzyme That Acetylates Cysteine S-Conjugates to Mercapturic Acids
Maria Veiga-da-Cunha et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
A protocol for generating a high-quality genome-scale metabolic reconstruction
Ines Thiele et al.
NATURE PROTOCOLS (2010)
A New Equation to Estimate Glomerular Filtration Rate
Andrew S. Levey et al.
ANNALS OF INTERNAL MEDICINE (2009)
Toward a Systems Level Understanding of Organic Anion and Other Multispecific Drug Transporters: A Remote Sensing and Signaling Hypothesis
Sun-Young Ahn et al.
MOLECULAR PHARMACOLOGY (2009)
Methods for detecting associations with rare variants for common diseases: Application to analysis of sequence data
Bingshan Li et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2008)
A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology
Markus J. Herrgard et al.
NATURE BIOTECHNOLOGY (2008)
Prevalence of chronic kidney disease in the United States
Josef Coresh et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2007)
Global reconstruction of the human metabolic network based on genomic and bibliomic data
Natalie C. Duarte et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
HMDB: the human metabolome database
David S. Wishart et al.
NUCLEIC ACIDS RESEARCH (2007)
Alterations in trans porter expression in liver, kidney, and duodenum after targeted disruption of the transcription factor HNF1α
J. M. Maher et al.
BIOCHEMICAL PHARMACOLOGY (2006)
Probabilistic quotient normalization as robust method to account for dilution of complex biological mixtures.: Application in 1H NMR metabonomics
Frank Dieterle et al.
ANALYTICAL CHEMISTRY (2006)
Mutations in SLC6A19, encoding B0AT1, cause Hartnup disorder
R Kleta et al.
NATURE GENETICS (2004)
Thirteen years of building constraint-based in silico models of Escherichia coli
JL Reed et al.
JOURNAL OF BACTERIOLOGY (2003)
L-2-hydroxyglutaric aciduria presenting as migraine
EH Kossoff et al.
NEUROLOGY (2001)