期刊
TRENDS IN NEUROSCIENCES
卷 44, 期 3, 页码 203-214出版社
CELL PRESS
DOI: 10.1016/j.tins.2020.10.016
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资金
- Inserm
- Fondation pour la Recherche Medicale [DEQ20160334919]
- La Marato de TV3 Fundacio [113-2016]
- Agence National de la Recherche [ANR-16-CE16-0018, ANR-16-CE16-0006]
- Universite de Paris
- Nutricia Research Foundation
- Allen Foundation Inc.
- Fyssen Foundation
- Agence Nationale de la Recherche (ANR) [ANR-16-CE16-0018, ANR-16-CE16-0006] Funding Source: Agence Nationale de la Recherche (ANR)
The dorsal striatum plays a critical role in controlling motor behaviors and recent studies have shown that the tail of striatum (TS) represents an additional functional domain with unique input-output connectivity, making it an integrator of sensory processing.
The dorsal striatum, the largest subcortical structure of the basal ganglia, is critical in controlling motor, procedural, and reinforcement-based behaviors. Although in mammals the striatum extends widely along the rostro-caudal axis, current knowledge and derived theories about its anatomo-functional organization largely rely on results obtained from studies of its rostral sectors, leading to potentially oversimplified working models of the striatum as a whole. Recent findings indicate that the extreme caudal part of the striatum, also referred to as the tail of striatum (TS), represents an additional functional domain. Here, we provide an overview of past and recent studies revealing that the TS displays a heterogeneous cell-type-specific organization, and a unique input-output connectivity, which poises the TS as an integrator of sensory processing.
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