4.7 Article

Plasma treated graphene FET sensor for the DNA hybridization detection

期刊

TALANTA
卷 223, 期 -, 页码 -

出版社

ELSEVIER
DOI: 10.1016/j.talanta.2020.121766

关键词

CVD graphene; Field-effect transistors; Plasma treatment; DNA hybridization detection; Charge neutral point

资金

  1. National Natural Science Foundation of China [11874244, 11974222]
  2. Key Technology Research and Development Program of Shandong (Key Technology R&D Program of Shandong Province) [2019GGX102048]

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This study introduces the usage of room-temperature plasma treated graphene based FET for DNA hybridization detection, showing improved affinity and electrical properties of the DNA-FET sensor through surface modification. The facile Ar plasma treatment effectively removes residues from the graphene surface and alters its hydrophilic properties, leading to enhanced performance of the DNA-FET sensor.
Room-temperature plasma treated graphene based FET was firstly proposed for the DNA hybridization detection. Affinity and electrical properties of the graphene based DNA-FET sensor were studied and improved benefits from the surface modification. The facile room-temperature Ar plasma easily removes residues from the graphene surface and changes the hydrophilic properties of graphene, which is important for our solution gated DNA-FET sensor. Limit of the detection of below 10 aM is obtained in our experiment. Especially, DNA concentration (C-DNA)/the amount of net drain current (Delta I) and the negative shift in the V-CNP value of the GFET sensor with the plasma treated 30 s are all improved compared with that without treatment. It shows that the easily plasma treatment of the graphene surface can be used for the solution gated FET sensor.

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