期刊
TALANTA
卷 223, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.talanta.2020.121689
关键词
Butylated hydroxyanisole; Electrochemical sensor; Gold nanoparticles; Molecularly imprinted polymer; Spectrophotometry; Food control
资金
- Moulay Ismail University of Meknes [2018]
- CNRST-Morocco
- Angstrom laboratory in Uppsala as part of the European project TROPSENSE under H2020-MSCA-RISE-2014 [645758]
This study presented a facile and fast synthesis approach for the development of an electrochemical sensor for BHA analysis by self-assembling chitosan with gold nanoparticles on a screen-printed carbon electrode. The molecularly imprinted polymer sensor demonstrated high sensitivity and selectivity to BHA in food samples. The sensor showed satisfactory performance in terms of detection range, detection limit, reproducibility, stability, and repeatability, making it a potential tool for food control.
One of the most widely used synthetic antioxidants in food, butylated hydroxyanisole (BHA) has raised serious concerns due to its potential toxic effects on human health. Hence, elaboration of simple, effective and sensitive methods for BHA detection is pressing. In this regards, the present research work highlights a facile, simple, and fast synthesis approach for the development of an electrochemical sensor for the analysis of BHA in foodstuffs. In this study, the chitosan (CS) capped with gold nanoparticles (AuNPs) were self-assembled on a screen-printed carbon electrode (SPCE) and complete the elaboration of the molecularly imprinted polymer (MIP) sensor in the presence of BHA as templates. The electrochemical behaviour of the MIP sensor was investigated by using electrochemical impedance spectroscopy (EIS), differential pulse voltammetry (DPV), and cyclic voltammetry (CV). Similarly, the morphology of the electrodes surface of the different elaboration steps was characterized by scanning electron microscopy (SEM), Fourier transform infrared (FTIR) spectroscopy, and atomic force microscopy (AFM). In addition, the obtained results demonstrate satisfactory sensitivity and selectivity to BHA compared to interfering species, including ascorbic acid and citric acid. Under optimal experimental conditions, the MIP sensor exhibits responses proportional to concentrations over a range of 0.01-20 mu g mL(-1), with a low detection limit (LOD) of 0.001 mu g mL(-1) (signal-to-noise ratio S/N = 3). Besides, the reproducibility, stability, and repeatability of the MIP sensor were proven. Taking into account all these outcomes, the MIP sensor well demonstrates its ability towards the determination of BHA in food samples with a relative standard deviation (RSD <= 8%). Spectrophotometry was utilized as a validation method. Partial least squares (PLS) prediction models were constructed from the MIP sensor and spectrophotometer data with a regression coefficient (R = 0.99). According to the achieved outcomes, the MIP sensor could be a viable tool for food control.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据