2-Hydroxynaphthalene based acylhydrazone as a turn-on fluorescent chemosensor for Al3+ detection and its real sample applications

Developing high performance fluorescent chemosensor for Al3+ detection is highly desirable, due to the excess of Al3+ will lead to many diseases. In this paper, a simple 2-hydroxynaphthalene-based fluorescent chemosensor has been synthesized and characterized by different spectroscopic methods. The compound exhibited an ``turn-on-type fluorescent chemosensing for the detection of Al3+, which was ascribed to the chelation-enhanced fluorescence (CHEF). The high selectivity and sensitivity of the compound for Al3+ were verified by fluorescence spectra in its DMF solution, and the enhancement of fluorescent intensity could be observed by naked-eye from non-fluorescence to green light. The detection limit of the compound for Al3+ was found to be 4.22 x 10(-8) M and the stability constant was 4.82 x 10(4) M-1. The 1:1 binding stoichiometry of the compound to Al3+ was confirmed from the Job's plot based on fluorescence titrations. Additionally, the sensing process of the compound to Al3+ was chemically reversible by adding Na(2)EDTA. Importantly, the probe was successfully applied to quantitative analysis of Al3+ in real drug and potable water samples. (C) 2020 Elsevier B.V. All rights reserved.

Automated summary

The synthesized fluorescent chemosensor showed high selectivity and sensitivity for Al3+, with a detection limit of 4.22 x 10(-8) M and a stability constant of 4.82 x 10(4) M-1. The 1:1 binding stoichiometry of the compound to Al3+ was confirmed from the Job's plot based on fluorescence titrations.