A novel near-infrared optical and redox-active receptor for the multi-model detection of Hg2+ in water and living cells

A key issue for constructing optical and redox-active receptors is how to conjugate a specific sensing kernel with a multi-signal-responsive system to carry out multi-feature analysis. Mercury is considered to be highly toxic to human health and ecological security. In this work, we present a novel near-infrared optical and redox-active receptor that can sense Hg2+ at ppb level in aqueous media via multi-model monitors with a low detection limit of 8.4 x 10(-9) M (1.68 ppb). This receptor features a visible detection, 'off-on' fluorescence response, and efficient electrochemistry assessment, as well as pH-insensitivity to Hg2+ with high sensitivity. In view of its marked near-infrared emission and fluorescence enhancement, we successfully applied this receptor to visualize Hg2+ in live cells. Furthermore, a possible sensing model was established and rationalized with theoretical studies. (C) 2020 Elsevier B.V. All rights reserved.

Automated summary

The novel near-infrared optical and redox-active receptor can detect Hg2+ in water at ppb level with low detection limit and multi-feature analysis functions, showing high sensitivity to Hg2+. A possible sensing model was established through theoretical studies.