4.8 Editorial Material

Superspreading genomes

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Article Multidisciplinary Sciences

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Summary: Analysis of 772 complete genomes of SARS-CoV-2 from early in the Boston-area epidemic shows multiple introductions of the virus, with two distinct superspreading events. One at a nursing facility resulted in rapid transmission and significant mortality, while the other at an international business conference led to sustained community transmission and widespread spread. The genetic variation generated by these events differed substantially, indicating varying transmission dynamics in superspreading events.

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