Response to Comment on Structural evidence for a dynamic metallocofactor during N2 reduction by Monitrogenase

Peters et al. comment on our report of the dynamic structure of the nitrogenase metallocofactor during N-2 reduction. Their claim that their independent structural refinement and consideration of biochemical data contradict our finding is incorrect and is strongly refuted by our biochemical and structural data that collectively and conclusively point to the binding of dinitrogen species to the nitrogenase cofactor.

Automated summary

Peters and colleagues' claim of contradicting our findings on the dynamic structure of the nitrogenase metallocofactor during N-2 reduction is refuted by our biochemical and structural data, which conclusively demonstrate the binding of dinitrogen species to the nitrogenase cofactor.