期刊
REVIEWS IN THE NEUROSCIENCES
卷 32, 期 6, 页码 615-629出版社
WALTER DE GRUYTER GMBH
DOI: 10.1515/revneuro-2020-0099
关键词
brain; epigenetics; improvement; neurotrophic factors; physical exercise; plasticity
资金
- National Science Foundation of China [81630038, 81971433, 81971428, 81771634, 81842011, 81330016, 81801629]
- National Key R&D Program of China [2017YFA 0104200]
- Ministry of Education of China [IRT0935]
- Science and Technology Bureau of Sichuan Province [2016TD0002]
- clinical discipline program (Neonatology) from the Ministry of Health of China [1311200003303]
- Fundamental Research Funds for the Central Universities
Exercise has been shown to have beneficial effects on brain functions, improving memory and learning, regulating epigenetics and neurogenesis, and enhancing cognitive function in animal models. This suggests that exercise can be used as a non-drug therapy for neurological diseases.
Exercise has been shown to have beneficial effects on brain functions in humans and animals. Exercise can improve memory and learning in age-related neurodegenerative diseases. In animal models, physical exercise regulates epigenetics, promotes synaptic plasticity and hippocampal neurogenesis, regulates the expression levels of neurotrophic factors, and improves cognitive function. Therefore, exercise is very important for brain rehabilitation and remodeling. The purpose of this review is to explore the mechanisms by which exercise exerts positive effects on brain function. This knowledge implies that physical exercise can be used as a non-drug therapy for neurological diseases.
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