期刊
ENVIRONMENT INTERNATIONAL
卷 97, 期 -, 页码 85-92出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.envint.2016.10.017
关键词
Adolescents; Air pollution; Hyperactivity; Inattention; Neurodevelopment
资金
- Marie Sklodowska-Curie Individual Fellowship (H2020-MSCA-IF) [704268]
- Federal Ministry for Education, Science, Research and Technology [01EG9705/2, 01EG9732]
- Helmholtz Zentrum Munich
- Federal Ministry for Environment (IUF) [FKZ 20462296]
- Federal Ministry for Education, Science, Research and Technology
- European Community's Seventh Framework Program (FP7) [211250]
- Commission of the European Communities
- 7th Framework Program (MeDALL project) [261357]
- Mead Johnson and Nestle companies (GINIplus)
- Marie Curie Actions (MSCA) [704268] Funding Source: Marie Curie Actions (MSCA)
Background: Few studies have examined the link between air pollution exposure and behavioural problems and learning disorders during late childhood and adolescence. Objectives: To determine whether traffic-related air pollution exposure is associated with hyperactivity/inattention, dyslexia and dyscalculia up to age 15 years using the German GINIplus and LISAplus birth cohorts (recruitment 1995-1999). Methods: Hyperactivity/inattentionwas assessed using the German parent-completed (10 years) and self-completed (15 years) Strengths and Difficulties Questionnaire. Responses were categorized into normal versus borderline/ abnormal. Parent-reported dyslexia and dyscalculia (yes/no) at age 10 and 15 years were defined using parent-completed questionnaires. Individual-level annual average estimates of nitrogen dioxide (NO2), particulate matter (PM)(10) mass, PM2.5 mass and PM2.5 absorbance concentrations were assigned to each participant's birth, 10 year and 15 year home address. Longitudinal associations between the air pollutants and the neurodevelopmental outcomes were assessed using generalized estimation equations, separately for both study areas, and combined in a random-effects meta-analysis. Odds ratios and 95% confidence intervals are given per interquartile range increase in pollutant concentration. Results: The prevalence of abnormal/borderline hyperactivity/inattention scores and parental-reported dyslexia and dyscalculia at 15 years of age was 12.9%, 10.5% and 3.4%, respectively, in the combined population (N=4745). In the meta-analysis, hyperactivity/inattention was associated with PM2.5 mass estimated to the 10 and 15 year addresses (1.12 [1.01, 1.23] and 1.11 [1.01, 1.22]) and PM2.5 absorbance estimated to the 10 and 15 year addresses (1.14 [1.05, 1.25] and 1.13 [1.04, 1.23], respectively). Conclusions: We report associations suggesting a potential link between air pollution exposure and hyperactivity/ inattention scores, although these findings require replication. (C) 2016 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据