Uterine artery Doppler to predict growth restriction in cases of abnormal first trimester analytes

We retrospectively included women with abnormal FTS analytes and compared outcomes between those with elevated and normal UtA PI. Out of 582 women with abnormal FTS analytes, 65 (11.2%) had elevated UtA PI. Neonates of women in this group had higher rates of birth weight <3rd, 5th, and 10th percentile. The area under the ROC curve for predicting FGR <10th percentile by UtA-PI was 0.584, for FGR<5th percentile 0.593, and for FGR<3rd percentile 0.720. In women with abnormal FTS, elevated UtA-PI is associated with higher rates of FGR, but its predictability is moderate-to-poor.

Automated summary

The study found that in women with abnormal FTS analytes, those with elevated UtA-PI are at increased risk of FGR. However, the predictability of FGR based on UtA-PI is moderate-to-poor.