期刊
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
卷 33, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.pdpdt.2020.102153
关键词
Olea cuspidata; Ag@MgO nanocomposites; Cytotoxicity; Photodegradation of methylene blue
类别
资金
- National Natural Science Foundation of China [21271017]
- National Science and Technology Supporting Plan of the Twelfth Five-year [2014BAE12B0101]
- Fundamental Research Funds for the Central Universities [XK1802-6]
- Deanship of Scientific Research at Najran University [NU/MID/17/043]
Green chemistry focuses on synthesizing nanomaterials using environmentally friendly techniques, with bimetallic nanoparticles showing promise in medicinal chemistry for disease treatment. The synthesized Ag@MgO nanocomposite exhibited strong antibacterial, photocatalytic, and antioxidant properties, showcasing the potential of green chemistry in developing multifunctional nanoparticles.
Green chemistry is a modern area of research which covers synthesis of nanomaterials through useful, envi-ronmentally, economically friendly techniques and their use in different fields. The synthesis involves the for-mation of bimetallic nanomaterials to enhance their synergistic relationship and achieve special modulated properties. That?s why bimetallic nanomaterials are extremely important and gaining interest among researchers in the field of medicinal chemistry for the treatment of various diseases. In this particular study, bimetallic nanoparticles synthesis was done by reduction procedure using leaf extract of Olea cuspidata. The phytochemicals in leaf extract act as stabilizing and capping agent in reduction of precursor's salts. The characterization of green synthesized Ag@MgO nanocomposite was done through several analytical techniques such as ultraviolet-visible (UV-vis) spectroscopy, X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), Scanning elec-tron microscope (SEM), High resolution transmission electron microscope (HRTEM) and Zeta potential. To explore the biological potential of synthesized nanocomposite, antibacterial activities against gram negative (Escherichia coli) bacteria and gram positive (Staphylococcus aureus) has been evaluated. The photocatalytic ac-tivity in contrary to methylene blue (MB) decomposition was seen efficiently. Moreover, the antioxidant nature of green synthesized Ag@MgO nanocomposite was analyzed by destabilizing and scavenging maximum per-centage (93 %) of dangerous and harmful 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free radical. The best and surprising results provided the information for the presence of essential and vital components in Olea Cuspidata in the form of organic acids (Citrus Acid) aids in stabilizing the entire structure with enhanced properties. Up to the best of our knowledge, the facts and results obtained regarding the structure of Ag@MgO nanocomposite clearly illustrates the uniqueness of green chemistry and also its role in future developing multifunctional nanoparticles in the field of nanobiotechnology.
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