Unraveling the C2-Symmetric Azatetraquinane System. Simple, Enantioselective Syntheses

Concise stereocontrolled synthetic routes to the C-2-symmetric azatetraquinane 1 (or, also, the enantiomer) are described. The successful execution of the synthesis involved innovation in the methodology for [3+2] cycloaddition and stereochemical control.

Automated summary

A concise stereocontrolled synthetic route to the C-2-symmetric azatetraquinane 1 (or its enantiomer) has been described, involving innovation in methodology for [3+2] cycloaddition and stereochemical control.