期刊
ORGANIC LETTERS
卷 23, 期 5, 页码 1572-1576出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.0c04281
关键词
-
资金
- MEXT [20H04818]
- Iketani Science and Technology Foundation
- JSPS
- Grants-in-Aid for Scientific Research [20H04818] Funding Source: KAKEN
This study reports on the N-heterocyclic carbene (NHC)-catalyzed Truce-Smiles rearrangement of aniline derivatives, where an unactivated C(aryl)-N bond is cleaved to form a new C(aryl)-C bond. The key to the success of this reaction lies in the utilization of highly nucleophilic NFIC, which enables the formation of a highly nucleophilic ylide intermediate generated from an alpha,beta-unsaturated amide.
We report on the N-heterocyclic carbene (NHC)-catalyzed Truce-Smiles rearrangement of aniline derivatives, in which an unactivated C(aryl)-N bond is cleaved, leading to the formation of a new C(aryl)-C bond. The key to the success of this reaction is the utilization of a highly nucleophilic NFIC, which enables the formation of a highly nucleophilic ylide intermediate that is generated from an alpha,beta-unsaturated amide.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据