Iron-Catalyzed α,β-Dehydrogenation of Carbonyl Compounds

An iron-catalyzed alpha,beta-dehydrogenation of carbonyl com-pounds was developed. A broad spectrum of carbonyls or analogues, such as aldehyde, ketone, lactone, lactam, amine, and alcohol, could be converted to their alpha,beta-unsaturated counterparts in a simple one-step reaction with high yields.

Automated summary

An iron-catalyzed alpha,beta-dehydrogenation reaction was developed for a broad spectrum of carbonyl compounds or analogues, providing a simple one-step conversion to their alpha,beta-unsaturated counterparts with high yields.