Dual modal plasmonic substrates based on a convective self-assembly technique for enhancement in SERS and LSPR detection

In this study, surface-enhanced Raman scattering (SERS) scheme is combined with localized surface plasmon resonance (LSPR) detection on a thin gold film with stripe patterns of gold nanoparticles (GNPs) via convective self-assembly (CSA) method. The potential of dual modal plasmonic substrates was evaluated by binding 4-ABT and IgG analytes, respectively. SERS experiments presented not only a high sensitivity with a detection limit of 4.7 nM and an enhancement factor of 1.34 x 10(5), but an excellent reproducibility with relative standard deviation of 5.5%. It was found from plasmonic sensing experiments by immobilizing IgG onto GNP-mediated gold film that detection sensitivity was improved by more than 211%, compared with a conventional bare gold film. Our synergistic SERS-LSPR approach based on a simple and cost-effective CSA method could open a route for sensitive, reliable and reproducible dual modal detection to expand the application areas. (C) 2021 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

Automated summary

In this study, a dual modal plasmonic substrate combining SERS and LSPR detection was evaluated using a CSA method, showing high sensitivity and excellent reproducibility. The detection sensitivity for IgG was improved by over 211% compared to a conventional gold film. The synergistic SERS-LSPR approach based on CSA could provide a sensitive, reliable, and reproducible dual modal detection for various applications.