期刊
NUCLEAR MEDICINE AND BIOLOGY
卷 93, 期 -, 页码 19-21出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.nucmedbio.2020.11.003
关键词
Nomenclature; Terminology; Consensus guidelines; Radiopharmaceutical sciences; Nuclear chemistry; Radiochemistry; Radiochemical conversion; Radiochemical yield
Radiochemical conversion is crucial in radiopharmaceutical chemistry, measuring the efficiency of reaction by studying the transformation of components in a crude reaction mixture. On the other hand, radiochemical yield is more suited to determining the efficiency of the entire reaction process, including separation, isolation, filtration, and formulation.
Radiochemical conversion is an important term to be included in the Consensus nomenclature rules for radiopharmaceutical chemistry. Radiochemical conversion should be used to define reaction efficiency by measuring the transformation of components in a crude reaction mixture at a given time, whereas radiochemical yield is better suited to define the efficiency of an entire reaction process including, for example, separation, isolation, filtration, and formulation. (C) 2020 Elsevier Inc. All rights reserved.
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