4.6 Article

Bioprocess intensification: Cases that (don't) work

期刊

NEW BIOTECHNOLOGY
卷 61, 期 -, 页码 108-115

出版社

ELSEVIER
DOI: 10.1016/j.nbt.2020.11.007

关键词

Techno-Economic assessment; Thermodynamic analysis; Integrated biobased manufacturing; Bioprocess intensification

资金

  1. Novo Nordisk Foundation, Denmark [NNF20SA0066233]

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The development of affordable and low carbon biobased manufacturing relies on strategies that reduce costs and emissions. This paper highlights the importance of minimizing operational expenditures in sustainable bio-economic development, and discusses the financial and climatic impacts of intensified and non-intensified biobased processes.
Development of affordable and low carbon biobased manufacturing depends critically on strategies that reduce cost and emission profiles. This paper indicates that efforts around the reduction of capital costs by intensification of process equipment need to be carefully weighed against the inherently fast increasing financial and climate costs of driving forces used for the intensification. The fundamental relation between capital expenditures (CAPEX) and operational expenditures (OPEX) of intensified and non-intensified biobased processes and their financial and climatic impacts are emphasized and provisionally explored for a few industrial processes. General learnings flag the importance in particular of OPEX minimisation for sustainable bio-economic development.

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