期刊
NEUROSURGERY
卷 88, 期 4, 页码 710-712出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/neuros/nyaa596
关键词
Bed nucleus of stria terminalis; Deep brain stimulation; Nucleus accumbens; Obsessive-compulsive disorder; Subthalamic nucleus
资金
- Congress of Neurological Surgeons
In 2020, a systematic review of literature on deep brain stimulation (DBS) for obsessive-compulsive disorder (OCD) was conducted to update the guidelines. Based on the data in the literature, recommendations were updated to include the use of bilateral subthalamic nucleus DBS or bilateral nucleus accumbens or bed nucleus of stria terminalis DBS for medically refractory OCD. There is insufficient evidence to determine the most effective target.
BACKGROUND: In 2020, the Guidelines Task Force conducted another systematic review of the relevant literature on deep brain stimulation (DBS) for obsessive-compulsive disorder (OCD) to update the original 2014 guidelines to ensure timeliness and accuracy for clinical practice. OBJECTIVE: To conduct a systematic review of the literature and update the evidencebased guidelines on DBS for OCD. METHODS: The Guidelines Task Force conducted another systematic review of the relevant literature, using the same search terms and strategies as used to search PubMed and Embase for relevant literature. The updated search included studies published between 1966 and December 2019. The same inclusion/exclusion criteria as the original guideline were also applied. Abstracts were reviewed and relevant full-text articles were retrieved and graded. Of 864 articles, 10 were retrieved for full-text review and analysis. Recommendations were updated according to new evidence yielded by this update. RESULTS: Seven studies were included in the original guideline, reporting the use of bilateral DBS as more effective in improving OCD symptoms than sham treatment. An additional 10 studies were included in this update: 1 class II and 9 class III. CONCLUSION: Based on the data published in the literature, the following recommendations can be made: (1) It is recommended that clinicians utilize bilateral subthalamic nucleus DBS over best medical management for the treatment of patients with medically refractory OCD (level I). (2) Cliniciansmay use bilateral nucleus accumbens or bed nucleus of stria terminalis DBS for the treatment of patientswithmedically refractory OCD (level II). There is insufficient evidence to make a recommendation for the identification of themost effective target. The full guidelines can be accessed at https://www.cns.org/guidelines/browse-guidelinesdetail/deep-brain-stimulation-obsessive-compulsive- disord.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据