相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Ten Unsolved Questions About Neuroinflammation in Parkinson's Disease
Etienne C. Hirsch et al.
MOVEMENT DISORDERS (2021)
The MHC class II transactivator modulates seeded alpha-synuclein pathology and dopaminergic neurodegeneration in an in vivo rat model of Parkinson's disease
Itzia Jimenez-Ferrer et al.
BRAIN BEHAVIOR AND IMMUNITY (2021)
Soluble CD163 Changes Indicate Monocyte Association With Cognitive Deficits in Parkinson's Disease
Sara Konstantin Nissen et al.
MOVEMENT DISORDERS (2021)
The Mast Cell Is an Early Activator of Lipopolysaccharide-Induced Neuroinflammation and Blood-Brain Barrier Dysfunction in the Hippocampus
Yiwei Wang et al.
MEDIATORS OF INFLAMMATION (2020)
Cerebrospinal Fluid Cytokines and Neurodegeneration-Associated Proteins in Parkinson's Disease
Ruwani S. Wijeyekoon et al.
MOVEMENT DISORDERS (2020)
Microglial exosomes facilitate α-synuclein transmission in Parkinson's disease
Min Guo et al.
BRAIN (2020)
Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells
Souvarish Sarkar et al.
FRONTIERS IN IMMUNOLOGY (2020)
Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain
Jinar Rostami et al.
JOURNAL OF NEUROINFLAMMATION (2020)
α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson's disease
Cecilia S. Lindestam Arlehamn et al.
NATURE COMMUNICATIONS (2020)
Microbiota Composition and Metabolism Are Associated With Gut Function in Parkinson's Disease
Mihai S. Cirstea et al.
MOVEMENT DISORDERS (2020)
Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models
Michiyo Iba et al.
JOURNAL OF NEUROINFLAMMATION (2020)
Mast Cell Activation, Neuroinflammation, and Tight Junction Protein Derangement in Acute Traumatic Brain Injury
Duraisamy Kempuraj et al.
MEDIATORS OF INFLAMMATION (2020)
Neuroinflammation and protein pathology in Parkinson's disease dementia
Antonina Kouli et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2020)
PARK14 (D331Y) PLA2G6 Causes Early-Onset Degeneration of Substantia Nigra Dopaminergic Neurons by Inducing Mitochondrial Dysfunction, ER Stress, Mitophagy Impairment and Transcriptional Dysregulation in a Knockin Mouse Model
Ching-Chi Chiu et al.
MOLECULAR NEUROBIOLOGY (2019)
LRRK2 links genetic and sporadic Parkinson's disease
Jillian H. Kluss et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2019)
Targeting -Synuclein in Parkinson's Disease: Progress Towards the Development of Disease-Modifying Therapeutics
Daniel Savitt et al.
DRUGS (2019)
Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia
Nikhil Panicker et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Development of an aggregate-selective, human-derived α-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models
Andreas Weihofen et al.
NEUROBIOLOGY OF DISEASE (2019)
Increased Immune Activation by Pathologic α-Synuclein in Parkinson's Disease
Veselin Grozdanov et al.
ANNALS OF NEUROLOGY (2019)
Altered gut microbiota and inflammatory cytokine responses in patients with Parkinson's disease
Chin-Hsien Lin et al.
JOURNAL OF NEUROINFLAMMATION (2019)
Randomized phase I clinical trial of anti-α-synuclein antibody BIIB054
Miroslaw Brys et al.
MOVEMENT DISORDERS (2019)
Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease
Sangjune Kim et al.
NEURON (2019)
Rifampicin and Its Derivative Rifampicin Quinone Reduce Microglial Inflammatory Responses and Neurodegeneration Induced In Vitro by α-Synuclein Fibrillary Aggregates
Leonardo Acuna et al.
CELLS (2019)
Alterations in Blood Monocyte Functions in Parkinson's Disease
Sara Konstantin Nissen et al.
MOVEMENT DISORDERS (2019)
Transcriptome analysis of LRRK2 knock-out microglia cells reveals alterations of inflammatory- and oxidative stress-related pathways upon treatment with α-synuclein fibrils
Isabella Russo et al.
NEUROBIOLOGY OF DISEASE (2019)
Dopamine receptor activation mitigates mitochondrial dysfunction and oxidative stress to enhance dopaminergic neurogenesis in 6-OHDA lesioned rats: A role of Wnt signalling
Akanksha Mishra et al.
NEUROCHEMISTRY INTERNATIONAL (2019)
Histamine-4 receptor antagonist JNJ7777120 inhibits pro-inflammatory microglia and prevents the progression of Parkinson-like pathology and behaviour in a rat model
Pei Zhou et al.
BRAIN BEHAVIOR AND IMMUNITY (2019)
Pathogenesis-targeted therapeutic strategies in Parkinson's disease
Joseph Jankovic
MOVEMENT DISORDERS (2019)
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
Mike A. Nalls et al.
LANCET NEUROLOGY (2019)
Triggers, Facilitators, and Aggravators: Redefining Parkinson's Disease Pathogenesis
Michaela E. Johnson et al.
TRENDS IN NEUROSCIENCES (2019)
Cross-Talk between Glia, Neurons and Mast Cells in Neuroinflammation Associated with Parkinson's Disease
Duraisamy Kempuraj et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2018)
The genetics of Parkinson disease
Hao Deng et al.
AGEING RESEARCH REVIEWS (2018)
Role of LRRK2 in manganese-induced neuroinflammation and microglial autophagy
Jiayan Chen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Th17 Lymphocytes Induce Neuronal Cell Death in a Human iPSC-Based Model of Parkinson's Disease
Annika Sommer et al.
CELL STEM CELL (2018)
Peripheral monocyte entry is required for alpha-Synuclein induced inflammation and Neurodegeneration in a model of Parkinson disease
Ashley S. Harms et al.
EXPERIMENTAL NEUROLOGY (2018)
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration (vol 15, 129, 2018)
Megan F. Duffy et al.
JOURNAL OF NEUROINFLAMMATION (2018)
Tolerogenic bone marrow-derived dendritic cells induce neuroprotective regulatory T cells in a model of Parkinson's disease
Charles R. Schutt et al.
MOLECULAR NEURODEGENERATION (2018)
Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson's disease
Seung Pil Yun et al.
NATURE MEDICINE (2018)
Cannabinoid CB1 and CB2 Receptors, and Monoacylglycerol Lipase Gene Expression Alterations in the Basal Ganglia of Patients with Parkinson's Disease
Francisco Navarrete et al.
NEUROTHERAPEUTICS (2018)
Mechanisms of Endogenous Neuroprotective Effects of Astrocytes in Brain Injury
Michelle A. Bylicky et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
Fecal markers of intestinal inflammation and intestinal permeability are elevated in Parkinson's disease
Andreas Schwiertz et al.
PARKINSONISM & RELATED DISORDERS (2018)
Anti-Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease
Inga Peter et al.
JAMA NEUROLOGY (2018)
Safety and Tolerability of Multiple Ascending Doses of PRX002/RG7935, an Anti-a-Synuclein Monoclonal Antibody, in Patients With Parkinson Disease A Randomized Clinical Trial
Joseph Jankovic et al.
JAMA NEUROLOGY (2018)
Mitochondrial Damage-Associated Molecular Patterns: From Inflammatory Signaling to Human Diseases
Serge Grazioli et al.
FRONTIERS IN IMMUNOLOGY (2018)
Immunosuppressants and risk of Parkinson disease
Brad A. Racette et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2018)
Immunogenetic Factors of Neurodegenerative Diseases: The Role of HLA Class II
M. P. Aliseychik et al.
BIOCHEMISTRY-MOSCOW (2018)
Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson's disease
Gregory P. Williams et al.
JOURNAL OF NEUROINFLAMMATION (2018)
Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation
Changyoun Kim et al.
MOLECULAR NEURODEGENERATION (2018)
Parkin and PINK1 mitigate STING-induced inflammation
Danielle A. Sliter et al.
NATURE (2018)
Reduced glucocerebrosidase activity in monocytes from patients with Parkinson's disease
Farzaneh Atashrazm et al.
SCIENTIFIC REPORTS (2018)
Antigen-presenting cell diversity for T cell reactivation in central nervous system autoimmunity
Ari Waisman et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2018)
Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice
Richard Gordon et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Immune Cell Activation in the Cerebrospinal Fluid of Patients With Parkinson's Disease
Jens B. Schroeder et al.
FRONTIERS IN NEUROLOGY (2018)
Monocyte Function in Parkinson's Disease and the Impact of Autologous Serum on Phagocytosis
Ruwani S. Wijeyekoon et al.
FRONTIERS IN NEUROLOGY (2018)
Th17 Cells Induce Dopaminergic Neuronal Death via LFA-1/ICAM-1 Interaction in a Mouse Model of Parkinson's Disease
Zhan Liu et al.
MOLECULAR NEUROBIOLOGY (2017)
Role of Microglia in Neurological Disorders and Their Potentials as a Therapeutic Target
Li Du et al.
MOLECULAR NEUROBIOLOGY (2017)
Peripheral immune tolerance alleviates the intracranial lipopolysaccharide injection-induced neuroinflammation and protects the dopaminergic neurons from neuroinflammation-related neurotoxicity
Yang Liu et al.
JOURNAL OF NEUROINFLAMMATION (2017)
Cerebrospinal Fluid Clearance in Alzheimer Disease Measured with Dynamic PET
Mony J. de Leon et al.
JOURNAL OF NUCLEAR MEDICINE (2017)
Glitazone Use Associated With Reduced Risk of Parkinson's Disease
Brage Brakedal et al.
MOVEMENT DISORDERS (2017)
Past, Present, and Future of Parkinson's Disease: A Special Essay on the 200th Anniversary of the Shaking Palsy
J. A. Obeso et al.
MOVEMENT DISORDERS (2017)
T cells from patients with Parkinson's disease recognize α-synuclein peptides
David Sulzer et al.
NATURE (2017)
Neurotoxic reactive astrocytes are induced by activated microglia
Shane A. Liddelow et al.
NATURE (2017)
A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci
Diana Chang et al.
NATURE GENETICS (2017)
Gut microbiota: Implications in Parkinson's disease
Arun Parashar et al.
PARKINSONISM & RELATED DISORDERS (2017)
Systemic Inflammation in Lewy Body Diseases A Systematic Review
Eleanor King et al.
ALZHEIMER DISEASE & ASSOCIATED DISORDERS (2017)
Mitochondrial DNA changes in pedunculopontine cholinergic neurons in Parkinson disease
Alexander G. Bury et al.
ANNALS OF NEUROLOGY (2017)
Cytokine networks in neuroinflammation
Burkhard Becher et al.
NATURE REVIEWS IMMUNOLOGY (2017)
Glymphatic MRI in idiopathic normal pressure hydrocephalus
Geir Ringstad et al.
BRAIN (2017)
Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases
Aree Witoelar et al.
JAMA NEUROLOGY (2017)
Evaluation of the safety and immunomodulatory effects of sargramostim in a randomized, double-blind phase 1 clinical Parkinson's disease trial
Howard E. Gendelman et al.
NPJ PARKINSONS DISEASE (2017)
Peroxisome proliferator-activated receptors (PPARs) as therapeutic target in neurodegenerative disorders
Swati Agarwal et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2017)
Microglial M1/M2 polarization and metabolic states
Ruben Orihuela et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
Linking a genome-wide association study signal to a LRRK2 coding variant in Parkinson's disease
Jia Nee Foo et al.
MOVEMENT DISORDERS (2016)
Extrastriatal spreading of microglial activation in Parkinson's disease: a positron emission tomography study
Tatsuhiro Terada et al.
ANNALS OF NUCLEAR MEDICINE (2016)
Cellular functions of LRRK2 implicate vesicular trafficking pathways in Parkinson's disease
Mark R. Cookson
BIOCHEMICAL SOCIETY TRANSACTIONS (2016)
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease
Timothy R. Sampson et al.
CELL (2016)
Parkinson's Disease-Related Proteins PINK1 and Parkin Repress Mitochondrial Antigen Presentation
Diana Matheoud et al.
CELL (2016)
Therapeutic anti-CD3 monoclonal antibodies: from bench to bedside
Chantal Kuhn et al.
IMMUNOTHERAPY (2016)
Inhibition of the JAK/STAT Pathway Protects Against α-Synuclein-Induced Neuroinflammation and Dopaminergic Neurodegeneration
Hongwei Qin et al.
JOURNAL OF NEUROSCIENCE (2016)
A polarizing question: do M1 and M2 microglia exist?
Richard M. Ransohoff
NATURE NEUROSCIENCE (2016)
Manganese-Enhanced Magnetic Resonance Imaging for Detection of Vasoactive Intestinal Peptide Receptor 2 Agonist Therapy in a Model of Parkinson's Disease
Katherine E. Olson et al.
NEUROTHERAPEUTICS (2016)
Cannabinoid Type 2 (CB2) Receptors Activation Protects against Oxidative Stress and Neuroinflammation Associated Dopaminergic Neurodegeneration in Rotenone Model of Parkinson's Disease
Hayate Javed et al.
FRONTIERS IN NEUROSCIENCE (2016)
CB2 receptor activation prevents glial-derived neurotoxic mediator production, BBB leakage and peripheral immune cell infiltration and rescues dopamine neurons in the MPTP model of Parkinson's disease
Young C. Chung et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2016)
Thiazolidinediones and Parkinson Disease: A Cohort Study
John G. Connolly et al.
AMERICAN JOURNAL OF EPIDEMIOLOGY (2015)
The methodology of TSPO imaging with positron emission tomography
Federico E. Turkheimer et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2015)
Pathogenic LRRK2 mutations, through increased kinase activity, produce enlarged lysosomes with reduced degradative capacity and increase ATP13A2 expression
Anastasia G. Henry et al.
HUMAN MOLECULAR GENETICS (2015)
Tanshinone I selectively suppresses pro-inflammatory genes expression in activated microglia and prevents nigrostriatal dopaminergic neurodegeneration in a mouse model of Parkinson's disease
Shaoxia Wang et al.
JOURNAL OF ETHNOPHARMACOLOGY (2015)
Dual Role of GM-CSF as a Pro-Inflammatory and a Regulatory Cytokine: Implications for Immune Therapy
Palash Bhattacharya et al.
JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2015)
Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy
Markus Mandler et al.
MOLECULAR NEURODEGENERATION (2015)
Colonic Bacterial Composition in Parkinson's Disease
Ali Keshavarzian et al.
MOVEMENT DISORDERS (2015)
Structural and functional features of central nervous system lymphatic vessels
Antoine Louveau et al.
NATURE (2015)
Host microbiota constantly control maturation and function of microglia in the CNS
Daniel Erny et al.
NATURE NEUROSCIENCE (2015)
Pathogenic Mechanisms of Neurodegeneration in Parkinson Disease
Stephen Mullin et al.
NEUROLOGIC CLINICS (2015)
Increased CSF biomarkers of angiogenesis in Parkinson disease
Shorena Janelidze et al.
NEUROLOGY (2015)
α-Asarone attenuates microglia-mediated neuroinflammation by inhibiting NF kappa B activation and mitigates MPTP-induced behavioral deficits in a mouse model of Parkinson's disease
Byung-Wook Kim et al.
NEUROPHARMACOLOGY (2015)
Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders
Stefano G. Daniele et al.
SCIENCE SIGNALING (2015)
In vivo characterization of microglial engulfment of dying neurons in the zebrafish spinal cord
Marco Morsch et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2015)
Glitazone Treatment and Incidence of Parkinson's Disease among People with Diabetes: A Retrospective Cohort Study
Ruth Brauer et al.
PLOS MEDICINE (2015)
Activation of MyD88-dependent TLR1/2 signaling by misfolded α-synuclein, a protein linked to neurodegenerative disorders
Stefano G. Daniele et al.
SCIENCE SIGNALING (2015)
The Role of LRRK2 in the Regulation of Monocyte Adhesion to Endothelial Cells
Li Hongge et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2015)
Next-generation active immunization approach for synucleinopathies: implications for Parkinson's disease clinical trials
Markus Mandler et al.
ACTA NEUROPATHOLOGICA (2014)
Tumour necrosis factor alpha-induced neuronal loss is mediated by microglial phagocytosis
Urte Neniskyte et al.
FEBS LETTERS (2014)
Soluble, Prefibrillar α-Synuclein Oligomers Promote Complex I-dependent, Ca2+-induced Mitochondrial Dysfunction
Eric S. Luth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Differential roles of microglia and monocytes in the inflamed central nervous system
Ryo Yamasaki et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease
Carmen Noelker et al.
JOURNAL OF NEUROINFLAMMATION (2014)
Reducing C-Terminal-Truncated Alpha-Synuclein by Immunotherapy Attenuates Neurodegeneration and Propagation in Parkinson's Disease-Like Models
Dora Games et al.
JOURNAL OF NEUROSCIENCE (2014)
Downregulation of Blood-Brain Barrier Phenotype by Proinflammatory Cytokines Involves NADPH Oxidase-Dependent ROS Generation: Consequences for Interendothelial Adherens and Tight Junctions
Keith D. Rochfort et al.
PLOS ONE (2014)
Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease
Alexandria Beilina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Proteomic analysis of human substantia nigra identifies novel candidates involved in Parkinson's disease pathogenesis
Virginie Licker et al.
PROTEOMICS (2014)
MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration
Carolina Cebrian et al.
NATURE COMMUNICATIONS (2014)
Association of Parkinson Disease with Structural and Regulatory Variants in the HLA Region
William T. Wissemann et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia
Lisa Fellner et al.
GLIA (2013)
MHCII Is Required for α-Synuclein-Induced Activation of Microglia, CD4 T Cell Proliferation, and Dopaminergic Neurodegeneratione
Ashley S. Harms et al.
JOURNAL OF NEUROSCIENCE (2013)
Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin
Wei Shao et al.
NATURE (2013)
Neuron-released oligomeric α-synuclein is an endogenous agonist of TLR2 for paracrine activation of microglia
Changyoun Kim et al.
NATURE COMMUNICATIONS (2013)
Brain-resident microglia predominate over infiltrating myeloid cells in activation, phagocytosis and interaction with T-lymphocytes in the MPTP mouse model of Parkinson disease
Candan Depboylu et al.
EXPERIMENTAL NEUROLOGY (2012)
CD4+Regulatory and Effector/Memory T Cell Subsets Profile Motor Dysfunction in Parkinson's Disease
Jessica A. Hutter Saunders et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2012)
Association between Parkinson's disease and the HLA-DRB1 locus
Ismail Ahmed et al.
MOVEMENT DISORDERS (2012)
A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β
Jeffrey J. Iliff et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Regulation of major histocompatibility complex class II genes
Nancy M. Choi et al.
CURRENT OPINION IN IMMUNOLOGY (2011)
Anti-CD3 Therapy Promotes Tolerance by Selectively Depleting Pathogenic Cells while Preserving Regulatory T Cells
Cristina Penaranda et al.
JOURNAL OF IMMUNOLOGY (2011)
The acute inflammatory response to intranigral α-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation
Yvonne Couch et al.
JOURNAL OF NEUROINFLAMMATION (2011)
The PPAR-γ agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys
Christine R. Swanson et al.
JOURNAL OF NEUROINFLAMMATION (2011)
A role for mitochondria in NLRP3 inflammasome activation
Rongbin Zhou et al.
NATURE (2011)
Use of ibuprofen and risk of Parkinson disease
Xiang Gao et al.
NEUROLOGY (2011)
alpha-Synuclein alters toll-like receptor expression
Dawn Beraud et al.
FRONTIERS IN NEUROSCIENCE (2011)
Parkinson's disease and immunological abnormalities: increase of HLA-DR expression on monocytes in cerebrospinal fluid and of CD45RO+ T cells in peripheral blood
U. Fiszer et al.
ACTA NEUROLOGICA SCANDINAVICA (2010)
Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1
Frits Kamp et al.
EMBO JOURNAL (2010)
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
I. Irrcher et al.
HUMAN MOLECULAR GENETICS (2010)
Five-Year Safety and Efficacy of Belatacept in Renal Transplantation
Flavio Vincenti et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
Taye H. Hamza et al.
NATURE GENETICS (2010)
Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2
Heather Mortiboys et al.
NEUROLOGY (2010)
MITOCHONDRIAL DNA IS RELEASED BY SHOCK AND ACTIVATES NEUTROPHILS VIA P38 MAP KINASE
Qin Zhang et al.
SHOCK (2010)
Candesartan inhibits Toll-like receptor expression and activity both in vitro and in vivo
Mohan R. Dasu et al.
ATHEROSCLEROSIS (2009)
Abatacept, a Novel CD80/86-CD28 T Cell Co-stimulation Modulator, in the Treatment of Rheumatoid Arthritis
Riku Korhonen et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2009)
Cross-regulation of Signaling Pathways by Interferon-γ: Implications for Immune Responses and Autoimmune Diseases
Xiaoyu Hu et al.
IMMUNITY (2009)
Nitrated α-Synuclein-Induced Alterations in Microglial Immunity Are Regulated by CD4+ T Cell Subsets
Ashley D. Reynolds et al.
JOURNAL OF IMMUNOLOGY (2009)
Neuroinflammation in Parkinson's disease: a target for neuroprotection?
Etienne C. Hirsch et al.
LANCET NEUROLOGY (2009)
Clearance and deposition of extracellular α-synuclein aggregates in microglia
He-Jin Lee et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Mitochondrial import and accumulation of α-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain
Latha Devi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Targeted Overexpression of Human α-Synuclein Triggers Microglial Activation and an Adaptive Immune Response in a Mouse Model of Parkinson Disease
Shaji Theodore et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)
Synuclein activates microglia in a model of Parkinson's disease
Xiaomin Su et al.
NEUROBIOLOGY OF AGING (2008)
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
Ira E. Clark et al.
NATURE (2006)
Expression levels of vascular endothelial growth factor and its receptors in Parkinson's disease
Keiichirou Wada et al.
NEUROREPORT (2006)
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
A Bender et al.
NATURE GENETICS (2006)
In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease
A Gerhard et al.
NEUROBIOLOGY OF DISEASE (2006)
Evidence that a significant number of naive T cells enter non-lymphoid organs as part of a normal migratory pathway
Stephen Cose et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2006)
Vasoactive intestinal peptide generates CD4+ CD25+ regulatory T cells in vivo
M Delgado et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2005)
Aggregated α-synuclein activates microglia:: a process leading to disease progression in Parkinson's disease
W Zhang et al.
FASEB JOURNAL (2005)
Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-lg with potent immunosuppressive properties
CP Larsen et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2005)
Blood-brain barrier dysfunction in Parkinsonian midbrain in vivo
R Kortekaas et al.
ANNALS OF NEUROLOGY (2005)
Alterations of T-lymphocyte populations in Parkinson disease
Y Baba et al.
PARKINSONISM & RELATED DISORDERS (2005)
Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease
EJ Benner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation
T Dehmer et al.
JOURNAL OF NEUROCHEMISTRY (2004)
分享论文
