Role of nutraceuticals in cognition during aging and related disorders

Cognitive abilities are compromised with advancing age posing a great risk for the development of dementia and other related brain disorders. Genetic susceptibility as well as environmental exposures determine the fate of cognitive aging and its transition to pathological states. Emerging epidemiological and observational studies have revealed the importance of lifestyle factors including dietary patterns and nutritional intake in the maintenance of cognitive health and reducing the risk of neurodegenerative disorders. In this context, nutraceutical interventions have gained considerable attention in preventing age-related cognitive deficits and counteracting pathological processes. Nutraceuticals include dietary plants and derivatives, food supplements and processed foods with nutritional and pharmaceutical values. The present review highlights the importance of nutraceuticals in attenuating cognitive aging and its progression to dementia, with specific emphasis on chemical constituents, neurocognitive properties and mechanism of action.

Automated summary

Cognitive abilities decline with age, posing a risk for the development of dementia and other brain disorders. Genetic susceptibility and environmental exposures determine the fate of cognitive aging and its progression to pathological states. Lifestyle factors, including dietary patterns and nutritional intake, are important in maintaining cognitive health and reducing the risk of neurodegenerative diseases.