相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。TSPO PET, tumour grading and molecular genetics in histologically verified glioma: a correlative 18F-GE-180 PET study
M. Unterrainer et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2020)
Improved detection of diffuse glioma infiltration with imaging combinations: a diagnostic accuracy study
Niels Verburg et al.
NEURO-ONCOLOGY (2020)
Imaging challenges of immunotherapy and targeted therapy in patients with brain metastases: response, progression, and pseudoprogression
Norbert Galldiks et al.
NEURO-ONCOLOGY (2020)
Simultaneous FET-PET and contrast-enhanced MRI based on hybrid PET/MR improves delineation of tumor spatial biodistribution in gliomas: a biopsy validation study
Shuangshuang Song et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2020)
Imaging glioma biology: spatial comparison of amino acid PET, amide proton transfer, and perfusion-weighted MRI in newly diagnosed gliomas
S. Schoen et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2020)
Spatial and quantitative mapping of glycolysis and hypoxia in glioblastoma as a predictor of radiotherapy response and sites of relapse
Antoine Leimgruber et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2020)
TSPO imaging-guided characterization of the immunosuppressive myeloid tumor microenvironment in patients with malignant glioma
Bastian Zinnhardt et al.
NEURO-ONCOLOGY (2020)
Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma
Annette M. Molinaro et al.
JAMA ONCOLOGY (2020)
Tyrosine Kinase Inhibitor Resistance Increased the Risk of Cerebral Radiation Necrosis After Stereotactic Radiosurgery in Brain Metastases of Non-small-Cell Lung Cancer: A Multi-Institutional Retrospective Case-Control Study
Hongqing Zhuang et al.
FRONTIERS IN ONCOLOGY (2020)
Recent advances of PET imaging in clinical radiation oncology
M. Unterrainer et al.
RADIATION ONCOLOGY (2020)
Margin reduction in radiotherapy for glioblastoma through 18F-fluoroethyltyrosine PET? - A recurrence pattern analysis
Daniel F. Fleischmann et al.
RADIOTHERAPY AND ONCOLOGY (2020)
Applications of radiomics and machine learning for radiotherapy of malignant brain tumors
Martin Kocher et al.
STRAHLENTHERAPIE UND ONKOLOGIE (2020)
Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions
Patrick Y. Wen et al.
NEURO-ONCOLOGY (2020)
Metabolic Tumor Volume Response Assessment Using (11)C-Methionine Positron Emission Tomography Identifies Glioblastoma Tumor Subregions That Predict Progression Better Than Baseline or Anatomic Magnetic Resonance Imaging Alone
Sean Miller et al.
ADVANCES IN RADIATION ONCOLOGY (2020)
O-(2-(18F) fluoroethyl)-L-tyrosine PET for the differentiation of tumour recurrence from late pseudoprogression in glioblastoma
Milena I. Mihovilovic et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2019)
Region-by-region analysis of PET, MRI, and histology in en bloc-resected oligodendrogliomas reveals intra-tumoral heterogeneity
Kenney Roy Roodakker et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2019)
Comparison of 18F-GE-180 and dynamic 18F-FET PET in high grade glioma: a double-tracer pilot study
Marcus Unterrainer et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2019)
Diffusion-weighted MRI and ADC versus FET-PET and GdT1w-MRI for gross tumor volume (GTV) delineation in re-irradiation of recurrent glioblastoma
Ilinca Popp et al.
RADIOTHERAPY AND ONCOLOGY (2019)
Dose-painted volumetric modulated arc therapy of high-grade glioma using 3,4-dihydroxy-6-[18F]fluoro-L-phenylalanine positron emission tomography
Robert Kosztyla et al.
BRITISH JOURNAL OF RADIOLOGY (2019)
Automated quantitative tumour response assessment of MRI in neuro-oncology with artificial neural networks: a multicentre, retrospective study
Philipp Kickingereder et al.
LANCET ONCOLOGY (2019)
Differentiation of treatment-related changes from tumour progression: a direct comparison between dynamic FET PET and ADC values obtained from DWI MRI
Jan-Michael Werner et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2019)
Potential for Nuclear Medicine Therapy for Glioblastoma Treatment
Clement Bailly et al.
FRONTIERS IN PHARMACOLOGY (2019)
Personalized Radiotherapy Design for Glioblastoma: Integrating Mathematical Tumor Models, Multimodal Scans, and Bayesian Inference
Jana Lipkova et al.
IEEE TRANSACTIONS ON MEDICAL IMAGING (2019)
Randomized Phase II Trial of Re-Irradiation and Concurrent Bevacizumab versus Bevacizumab Alone as Treatment for Recurrent Glioblastoma (NRG Oncology/RTOG 1205): Initial Outcomes and RT Plan Quality Report
C. Tsien et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2019)
DIAGNOSIS OF PSEUDOPROGRESSION USING FET PET RADIOMICS
P. Lohmann et al.
NEURO-ONCOLOGY (2019)
Recurrent glioblastoma versus late posttreatment changes: diagnostic accuracy of O-(2-[18F]fluoroethyl)-L-tyrosine positron emission tomography (18F-FET PET)
Asma Bashir et al.
NEURO-ONCOLOGY (2019)
Imaging Glioblastoma Posttreatment Progression, Pseudoprogression, Pseudoresponse, Radiation Necrosis
Sara B. Strauss et al.
RADIOLOGIC CLINICS OF NORTH AMERICA (2019)
FET PET reveals considerable spatial differences in tumour burden compared to conventional MRI in newly diagnosed glioblastoma
Philipp Lohmann et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2019)
Joint EANM/EANO/RANO practice guidelines/SNMMI procedure standards for imaging of gliomas using PET with radiolabelled amino acids and [18F]FDG: version 1.0
Ian Law et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2019)
Deep learning in medical imaging and radiation therapy
Berkman Sahiner et al.
MEDICAL PHYSICS (2019)
PET imaging in patients with brain metastasis-report of the RANO/PET group
Norbert Galldiks et al.
NEURO-ONCOLOGY (2019)
Diagnosis of glioma recurrence using multiparametric dynamic 18F-fluoroethyl-tyrosine PET-MRI
Thomas Pyka et al.
EUROPEAN JOURNAL OF RADIOLOGY (2018)
C11 Methionine PET (MET-PET) Imaging of Glioblastoma for Detecting Postoperative Residual Disease and Response to Chemoradiation Therapy
Yingbing Wang et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2018)
Investigating the Effect of Reirradiation or Systemic Therapy in Patients With Glioblastoma After Tumor Progression: A Secondary Analysis of NRG Oncology/Radiation Therapy Oncology Group Trial 0525
Wenyin Shi et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2018)
Automatic lesion detection and segmentation of 18F-FET PET in gliomas: A full 3D U-Net convolutional neural network study
Paul Blanc-Durand et al.
PLOS ONE (2018)
Independent validation of a new reirradiation risk score (RRRS) for glioma patients predicting post-recurrence survival: A multicenter DKTK/ROG analysis
Maximilian Niyazi et al.
RADIOTHERAPY AND ONCOLOGY (2018)
Impact of 18F-FET PET on Target Volume Definition and Tumor Progression of Recurrent High Grade Glioma Treated with Carbon-Ion Radiotherapy
Charlotte Debus et al.
SCIENTIFIC REPORTS (2018)
Immunotherapy and Symptomatic Radiation Necrosis in Patients With Brain Metastases Treated With Stereotactic Radiation
Allison M. Martin et al.
JAMA ONCOLOGY (2018)
Combined FET PET/MRI radiomics differentiates radiation injury from recurrent brain metastasis
Philipp Lohmann et al.
NEUROIMAGE-CLINICAL (2018)
ACTR-12. PRELIMINARY SAFETY AND EFFICACY OF A PHASE II TRIAL OF 18F-DOPA PET-GUIDED, DOSE-ESCALATED RADIOTHERAPY IN THE TREATMENT OF GLIOBLASTOMA
Nadia Laack et al.
NEURO-ONCOLOGY (2018)
Utilizing 18F-fluoroethyltyrosine (FET) positron emission tomography (PET) to define suspected nonenhancing tumor for radiation therapy planning of glioblastoma
Aimee R. Hayes et al.
PRACTICAL RADIATION ONCOLOGY (2018)
The prognostic value of FET PET at radiotherapy planning in newly diagnosed glioblastoma
Sidsel Hojklint Poulsen et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2017)
TSPO PET for glioma imaging using the novel ligand 18F-GE-180: first results in patients with glioblastoma
Nathalie L. Albert et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2017)
[18F]-FMISO PET study of hypoxia in gliomas before surgery: correlation with molecular markers of hypoxia and angiogenesis
Lien Bekaert et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2017)
18F-FET PET prior to recurrent high-grade glioma re-irradiation-additional prognostic value of dynamic time-to-peak analysis and early static summation images?
Daniel F. Fleischmann et al.
JOURNAL OF NEURO-ONCOLOGY (2017)
European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas
Michael Weller et al.
LANCET ONCOLOGY (2017)
Advances in neuro-oncology imaging
Karl-Josef Langen et al.
NATURE REVIEWS NEUROLOGY (2017)
The Neurologic Assessment in Neuro-Oncology (NANO) scale: a tool to assess neurologic function for integration into the Response Assessment in Neuro-Oncology (RANO) criteria
Lakshmi Nayak et al.
NEURO-ONCOLOGY (2017)
PET imaging in patients with meningioma-report of the RANO/PET Group
Norbert Galldiks et al.
NEURO-ONCOLOGY (2017)
Lomustine and Bevacizumab in Progressive Glioblastoma
Wolfgang Wick et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Toxicity and efficacy of re-irradiation of high-grade glioma in a phase I dose- and volume escalation trial
Soren Moller et al.
RADIOTHERAPY AND ONCOLOGY (2017)
Brain Tumors: An Update on Clinical PET Research in Gliomas
Karl Herholz
SEMINARS IN NUCLEAR MEDICINE (2017)
Late Pseudoprogression in Glioblastoma: Diagnostic Value of Dynamic O-(2-[18F]fluoroethyl)-L-Tyrosine PET
Sied Kebir et al.
CLINICAL CANCER RESEARCH (2016)
Re-irradiation for Recurrent Primary Brain Tumors
Carsten Nieder et al.
ANTICANCER RESEARCH (2016)
Amino-acid PET versus MRI guided re-irradiation in patients with recurrent glioblastoma multiforme (GLIAA) - protocol of a randomized phase II trial (NOA 10/ARO 2013-1)
Oliver Oehlke et al.
BMC CANCER (2016)
Does immunotherapy increase the rate of radiation necrosis after radiosurgical treatment of brain metastases?
Rovel J. Colaco et al.
JOURNAL OF NEUROSURGERY (2016)
Response Assessment in Neuro-Oncology working group and European Association for Neuro-Oncology recommendations for the clinical use of PET imaging in gliomas
Nathalie L. Albert et al.
NEURO-ONCOLOGY (2016)
Relapse patterns after radiochemotherapy of glioblastoma with FET PET-guided boost irradiation and simulation to optimize radiation target volume
Marc D. Piroth et al.
RADIATION ONCOLOGY (2016)
ESTRO-ACROP guideline target delineation of glioblastomas
Maximilian Niyazi et al.
RADIOTHERAPY AND ONCOLOGY (2016)
Study of LAT1 Expression in Brain Metastases: Towards a Better Understanding of the Results of Positron Emission Tomography Using Amino Acid Tracers
Caroline Papin-Michault et al.
PLOS ONE (2016)
Biological tumor volume in 18FET-PET before radiochemotherapy correlates with survival in GBM
Bogdana Suchorska et al.
NEUROLOGY (2015)
Diagnosis of pseudoprogression in patients with glioblastoma using O-(2-[18F]fluoroethyl)-L-tyrosine PET
Norbert Galldiks et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2015)
Impact of [18F]-fluoro-ethyl-tyrosine PET imaging on target definition for radiation therapy of high-grade glioma
Per Munck af Rosenschold et al.
NEURO-ONCOLOGY (2015)
Phase II Study of Bevacizumab, Temozolomide, and Hypofractionated Stereotactic Radiotherapy for Newly Diagnosed Glioblastoma
Antonio Omuro et al.
CLINICAL CANCER RESEARCH (2014)
Comparison of the Amino Acid Tracers 18F-FET and 18F-DOPA in High-Grade Glioma Patients
Constantin Lapa et al.
JOURNAL OF NUCLEAR MEDICINE (2014)
Comparison of visual and semiquantitative analysis of 18F-FDOPA-PET/CT for recurrence detection in glioblastoma patients
Ken Herrmann et al.
NEURO-ONCOLOGY (2014)
Re-irradiation of recurrent glioblastoma multiforme using 11C-methionine PET/CT/MRI image fusion for hypofractionated stereotactic radiotherapy by intensity modulated radiation therapy
Kazuhiro Miwa et al.
RADIATION ONCOLOGY (2014)
Hypofractionated High-Dose Irradiation with Positron Emission Tomography Data for the Treatment of Glioblastoma Multiforme
Kazuhiro Miwa et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Diagnostic Accuracy of PET for Recurrent Glioma Diagnosis: A Meta-Analysis
T. Nihashi et al.
AMERICAN JOURNAL OF NEURORADIOLOGY (2013)
18F-FDOPA PET/CT for detection of recurrence in patients with glioma: prospective comparison with 18F-FDG PET/CT
Sellam Karunanithi et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2013)
Comparative diagnostic accuracy of contrast-enhanced MRI and 18F-FDOPA PET-CT in recurrent glioma
Sellam Karunanithi et al.
EUROPEAN RADIOLOGY (2013)
High-Grade Glioma Radiation Therapy Target Volumes and Patterns of Failure Obtained From Magnetic Resonance Imaging and 18F-FDOPA Positron Emission Tomography Delineations From Multiple Observers
Robert Kosztyla et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2013)
Biopsy validation of 18F-DOPA PET and biodistribution in gliomas for neurosurgical planning and radiotherapy target delineation: results of a prospective pilot study
Deanna H. Pafundi et al.
NEURO-ONCOLOGY (2013)
Analysis of FET-PET imaging for target volume definition in patients with gliomas treated with conformal radiotherapy
Stefan Rieken et al.
RADIOTHERAPY AND ONCOLOGY (2013)
[18F]Fluoroethyltyrosine-Positron Emission Tomography-Based Therapy Monitoring after Stereotactic Iodine-125 Brachytherapy in Patients with Recurrent High-Grade Glioma
Nathalie L. Jansen et al.
MOLECULAR IMAGING (2013)
IMPACT OF [C-11]METHIONINE POSITRON EMISSION TOMOGRAPHY FOR TARGET DEFINITION OF GLIOBLASTOMA MULTIFORME IN RADIATION THERAPY PLANNING
Masayuki Matsuo et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2012)
Independent prognostic value of pre-treatment 18-FDG-PET in high-grade gliomas
Cecile Colavolpe et al.
JOURNAL OF NEURO-ONCOLOGY (2012)
Re-irradiation in recurrent malignant glioma: prognostic value of [18F]FET-PET
Maximilian Niyazi et al.
JOURNAL OF NEURO-ONCOLOGY (2012)
Transport of 3-Fluoro-L-α-Methyl-Tyrosine by Tumor-Upregulated L-Type Amino Acid Transporter 1: A Cause of the Tumor Uptake in PET
Pattama Wiriyasermkul et al.
JOURNAL OF NUCLEAR MEDICINE (2012)
Accurate Differentiation of Recurrent Gliomas from Radiation Injury by Kinetic Analysis of α-11C-Methyl-L-Tryptophan PET
Balint Alkonyi et al.
JOURNAL OF NUCLEAR MEDICINE (2012)
Assessment of Treatment Response in Patients with Glioblastoma Using O-(2-18F-Fluoroethyl)-L-Tyrosine PET in Comparison to MRI
Norbert Galldiks et al.
JOURNAL OF NUCLEAR MEDICINE (2012)
Integrated boost IMRT with FET-PET-adapted local dose escalation in glioblastomas Results of a prospective phase II study
M. D. Piroth et al.
STRAHLENTHERAPIE UND ONKOLOGIE (2012)
AN INTERINDIVIDUAL COMPARISON OF O-(2-[18F]FLUOROETHYL)-L-TYROSINE (FET)- AND L-[METHYL-11C]METHIONINE (MET)-PET IN PATIENTS WITH BRAIN GLIOMAS AND METASTASES
Anca-Ligia Grosu et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2011)
PROGNOSTIC VALUE OF EARLY [18F]FLUOROETHYLTYROSINE POSITRON EMISSION TOMOGRAPHY AFTER RADIOCHEMOTHERAPY IN GLIOBLASTOMA MULTIFORME
Marc D. Piroth et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2011)
RANDOMIZED DOUBLE-BLIND PLACEBO-CONTROLLED TRIAL OF BEVACIZUMAB THERAPY FOR RADIATION NECROSIS OF THE CENTRAL NERVOUS SYSTEM
Victor A. Levin et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2011)
Hot spots in dynamic 18FET-PET delineate malignant tumor parts within suspected WHO grade II gliomas
M. Kunz et al.
NEURO-ONCOLOGY (2011)
FET-PET for malignant glioma treatment planning
Maximilian Niyazi et al.
RADIOTHERAPY AND ONCOLOGY (2011)
Updated Response Assessment Criteria for High-Grade Gliomas: Response Assessment in Neuro-Oncology Working Group
Patrick Y. Wen et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
ASSOCIATION OF 11C-METHIONINE PET UPTAKE WITH SITE OF FAILURE AFTER CONCURRENT TEMOZOLOMIDE AND RADIATION FOR PRIMARY GLIOBLASTOMA MULTIFORME
Irwin H. Lee et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2009)
Recurrence pattern after [(18)F]Fluoroethyltyrosine-Positron Emission Tomography-guided radiotherapy for high-grade glioma: A prospective study
Damien C. Weber et al.
RADIOTHERAPY AND ONCOLOGY (2009)
L-[methyl-11C] methionine positron emission tomography for target delineation in malignant gliomas:: Impact on results of carbon ion radiotherapy
Pawinee Mahasittiwat et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2008)
Correlative imaging of hypoxia and angiogenesis in oncology
Karl Josef Langen et al.
JOURNAL OF NUCLEAR MEDICINE (2008)
Diagnostic accuracy of 11C-methionine PET for differentiation of recurrent brain tumors from radiation necrosis after radiotherapy
Yuzo Terakawa et al.
JOURNAL OF NUCLEAR MEDICINE (2008)
Clinical features, mechanisms, and management of pseudoprogression in malignant gliomas
Dieto Brandsma et al.
LANCET ONCOLOGY (2008)
[(18)F]Fluoroethyltyrosine- positron emission tomography-guided radiotherapy for high-grade glioma
Damien C. Weber et al.
RADIATION ONCOLOGY (2008)
Differential uptake of O-(2-18F-fluoroethyl)-L-tyrosine, L-3H-methionine, and 3H-deoxyglucose in brain abscesses
Daumar Salber et al.
JOURNAL OF NUCLEAR MEDICINE (2007)
Spatial normalization of lesioned brains: Performance evaluation and impact on fMRI analyses
Jenny Crinion et al.
NEUROIMAGE (2007)
Early change in glucose metabolic rate measured using FDG-PET in patients with high-grade glioma predicts response to temozolomide but not temozolomide plus radiotherapy
Natalie Charnley et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2006)
Cerebral radiation necrosis: Incidence, outcomes, and risk factors with emphasis on radiation parameters and chemotherapy
Jeremy D. Ruben et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2006)
[F-18]-fluorodeoxyglucose positron emission tomography for targeting radiation dose escalation for patients with glioblastoma multiforme: Clinical outcomes and patterns of failure
JG Douglas et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2006)
Reirradiation of recurrent high-grade gliomas using amino acid PET (SPECT)/CT/MRI image fusion to determine gross tumor volume for stereotactic fractionated radiotherapy
AL Grosu et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2005)
O-(2-[18F]fluoroethyl)-L-tyrosine PET combined with MRI improves the diagnostic assessment of cerebral gliomas
D Pauleit et al.
BRAIN (2005)
L-(methyl-11C) methionine positron emission tomography for target delineation in resected high-grade gliomas before radiotherapy
AL Grosu et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2005)
Delineation of brain tumor extent with [11C]L-methionine positron emission tomography:: Local comparison with stereotactic histopathology
LW Kracht et al.
CLINICAL CANCER RESEARCH (2004)
Brain tumour imaging with PET:: a comparison between [18F]fluorodopa and [11C]methionine
A Becherer et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2003)
Malignant gliomas: MR imaging spectrum of radiation therapy- and chemotherapy-induced necrosis of the brain after treatment
AJ Kumar et al.
RADIOLOGY (2000)
Radiotherapy treatment planning and long-term follow-up with [11C]methionine pet in patients with low-grade astrocytoma
J Nuutinen et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2000)