期刊
NEURAL COMPUTING & APPLICATIONS
卷 33, 期 16, 页码 10415-10428出版社
SPRINGER LONDON LTD
DOI: 10.1007/s00521-021-05799-w
关键词
AD-classification; Convolutional neural network (CNN); Magnetic resonance imaging (MRI); Adaptive momentum estimation (Adam); Glorot uniform weight initializer
With advances in healthcare, the diagnosis of Alzheimer's disease has become increasingly important. Studies utilizing brain MRI scans and deep learning algorithms have shown promising results, aiding in the early and accurate classification of Alzheimer's disease.
In the current decade, advances in health care are attracting widespread interest due to their contributions to people longer surviving and fitter lives. Alzheimer's disease (AD) is the commonest neurodegenerative and dementing disease. The monetary value of caring for Alzheimer's disease patients is involved to rise dramatically. The necessity of having a computer-aided system for early and accurate AD classification becomes crucial. Deep-learning algorithms have notable advantages rather than machine learning methods. Many recent research studies that have used brain MRI scans and convolutional neural networks (CNN) achieved promising results for the diagnosis of Alzheimer's disease. Accordingly, this study proposes a CNN based end-to-end framework for AD-classification. The proposed framework achieved 99.6%, 99.8%, and 97.8% classification accuracies on Alzheimer's disease Neuroimaging Initiative (ADNI) dataset for the binary classification of AD and Cognitively Normal (CN). In multi-classification experiments, the proposed framework achieved 97.5% classification accuracy on the ADNI dataset.
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