相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Pan-cancer analysis of NLRP3 inflammasome with potential implications in prognosis and immunotherapy in human cancer
Mingyi Ju et al.
BRIEFINGS IN BIOINFORMATICS (2021)
Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes
Rajendra Karki et al.
CELL (2021)
Tumor Cell-Derived IL1β Promotes Desmoplasia and Immune Suppression in Pancreatic Cancer
Shipra Das et al.
CANCER RESEARCH (2020)
Inflammasomes and the fine line between defense and disease
Shelbi Christgen et al.
CURRENT OPINION IN IMMUNOLOGY (2020)
Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity-independent pyroptosis, apoptosis, necroptosis, and inflammatory disease
R. K. Subbarao Malireddi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
Min Zheng et al.
CELL (2020)
Toward targeting inflammasomes: insights into their regulation and activation
Shelbi Christgen et al.
CELL RESEARCH (2020)
The Z?2 domain of ZBP1 is a molecular switch regulating influenza-induced PANoptosis and perinatal lethality during development
Sannula Kesavardhana et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy
Balamayoora Theivanthiran et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
IRF8 Regulates Gram-Negative Bacteria-Mediated NLRP3 Inflammasome Activation and Cell Death
Rajendra Karki et al.
JOURNAL OF IMMUNOLOGY (2020)
Chemotherapy-induced pyroptosis is mediated by BAK/BAX-caspase-3-GSDME pathway and inhibited by 2-bromopalmitate
Lei Hu et al.
CELL DEATH & DISEASE (2020)
Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis)
Shelbi Christgen et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2020)
Interferon regulatory factor 1 regulates PANoptosis to prevent colorectal cancer
Rajendra Karki et al.
JCI INSIGHT (2020)
PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis
Junwei Hou et al.
NATURE CELL BIOLOGY (2020)
Cell Death in Liver Diseases: A Review
Layla Shojaie et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Galactosaminogalactan activates the inflammasome to provide host protection
Benoit Briard et al.
NATURE (2020)
Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation
Mercedes Segovia et al.
CANCER CELL (2019)
Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome
Humayun Sharif et al.
NATURE (2019)
DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome
Parimal Samir et al.
NATURE (2019)
Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis
Christina D. Camell et al.
CELL METABOLISM (2019)
Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer
Oxana Dmitrieva-Posocco et al.
IMMUNITY (2019)
Diverging inflammasome signals in tumorigenesis and potential targeting
Rajendra Karki et al.
NATURE REVIEWS CANCER (2019)
The NLRP3 inflammasome in acute myocardial infarction
Stefano Toldo et al.
NATURE REVIEWS CARDIOLOGY (2018)
NLRP3 Inflammasome and the IL-1 Pathway in Atherosclerosis
Alena Grebe et al.
CIRCULATION RESEARCH (2018)
Pyrin Inflammasome Regulates Tight Junction Integrity to Restrict Colitis and Tumorigenesis
Deepika Sharma et al.
GASTROENTEROLOGY (2018)
The genetic polymorphism and expression profiles of NLRP3 inflammasome in patients with chronic myeloid leukemia
Amin Zhang et al.
HUMAN IMMUNOLOGY (2018)
TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation
R. K. Subbarao Malireddi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2018)
Adipocyte-derived Lysophosphatidylcholine Activates Adipocyte and Adipose Tissue Macrophage Nod-Like Receptor Protein 3 Inflammasomes Mediating Homocysteine-Induced Insulin Resistance
Song-Yang Zhang et al.
EBIOMEDICINE (2018)
Blockage of the NLRP3 inflammasome by MCC950 improves anti-tumor immune responses in head and neck squamous cell carcinoma
Lei Chen et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Inflammasome activation and assembly at a glance
Ankit Malik et al.
JOURNAL OF CELL SCIENCE (2017)
NLRP3 signaling drives macrophage-induced adaptive immune suppression in pancreatic carcinoma
Donnele Daley et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial
Paul M. Ridker et al.
LANCET (2017)
Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing
Christina D. Camell et al.
NATURE (2017)
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
Yupeng Wang et al.
NATURE (2017)
Inflammation, metaflammation and immunometabolic disorders
Gokhan S. Hotamisligil
NATURE (2017)
Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
P. M. Ridker et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis
Xiaomin Yao et al.
NATURE COMMUNICATIONS (2017)
P2X7 receptor and NLRP3 inflammasome activation in head and neck cancer
Ju Young Bae et al.
ONCOTARGET (2017)
NLRP3 inflammasome activation plays a carcinogenic role through effector cytokine IL-18 in lymphoma
Xia Zhao et al.
ONCOTARGET (2017)
Microbiota Normalization Reveals that Canonical Caspase-1 Activation Exacerbates Chemically Induced Intestinal Inflammation
Adrian J. Blazejewski et al.
CELL REPORTS (2017)
Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation
Erez Dror et al.
NATURE IMMUNOLOGY (2017)
A Role of the Inflammasome in the Low Storage Capacity of the Abdominal Subcutaneous Adipose Tissue in Obese Adolescents
Romy Kursawe et al.
DIABETES (2016)
NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component
Hexin Shi et al.
NATURE IMMUNOLOGY (2016)
Dietary cholesterol promotes AOM-induced colorectal cancer through activating the NLRP3 inflammasome
Qianming Du et al.
BIOCHEMICAL PHARMACOLOGY (2016)
IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes
Si Ming Man et al.
CELL (2016)
Human Monocytes Engage an Alternative Inflammasome Pathway
Moritz M. Gaidt et al.
IMMUNITY (2016)
The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulation
Deepika Sharma et al.
JOURNAL OF CELL BIOLOGY (2016)
NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22
Marianne R. Spalinger et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer
Rajendra Karki et al.
NATURE (2016)
NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
Yuan He et al.
NATURE (2016)
Loss of Nlrp3 Does Not Protect Mice from Western Diet-Induced Adipose Tissue Inflammation and Glucose Intolerance
Rebecca E. Ringling et al.
PLOS ONE (2016)
NLRP3 inflammasome plays a redundant role with caspase 8 to promote IL-1β-mediated osteomyelitis
Prajwal Gurung et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Obesity and Type 2 Diabetes Alters the Immune Properties of Human Adipose Derived Stem Cells
Carolina Serena et al.
STEM CELLS (2016)
Saturated Fatty Acids Engage an IRE1α-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells
Megan M. Robblee et al.
CELL REPORTS (2016)
Targeting inflammasome/IL-1 pathways for cancer immunotherapy
Beichu Guo et al.
SCIENTIFIC REPORTS (2016)
ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways
Teneema Kuriakose et al.
SCIENCE IMMUNOLOGY (2016)
Human Lung Cancer-Derived Immunosuppressive Plasmacytoid Dendritic Cells Release IL-1α in an AIM2 Inflammasome-Dependent Manner
Rosalinda Sorrentino et al.
AMERICAN JOURNAL OF PATHOLOGY (2015)
The Q705K and F359L Single-Nucleotide Polymorphisms of NOD-Like Receptor Signaling Pathway: Association with Chronic Pancreatitis, Pancreatic Cancer, and Periodontitis
Andrzej Miskiewicz et al.
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS (2015)
Expression of NLRP3 in subcutaneous adipose tissue is associated with coronary atherosclerosis
Sachiko Bando et al.
ATHEROSCLEROSIS (2015)
Concerted Activation of the AIM2 and NLRP3 Inflammasomes Orchestrates Host Protection against Aspergillus Infection
Rajendra Karki et al.
CELL HOST & MICROBE (2015)
Monounsaturated Fatty Acid-Enriched High-Fat Diets Impede Adipose NLRP3 Inflammasome-Mediated IL-1β Secretion and Insulin Resistance Despite Obesity
Orla M. Finucane et al.
DIABETES (2015)
Bone marrow-specific caspase-1/11 deficiency inhibits atherosclerosis development in Ldlr-/- mice
Tim Hendrikx et al.
FEBS JOURNAL (2015)
The Nlrp3 Inflammasome Suppresses Colorectal Cancer Metastatic Growth in the Liver by Promoting Natural Killer Cell Tumoricidal Activity
Jeremy Dupaul-Chicoine et al.
IMMUNITY (2015)
Macrophage-specific de Novo Synthesis of Ceramide Is Dispensable for Inflammasome-driven Inflammation and Insulin Resistance in Obesity
Christina D. Camell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Cutting Edge: SHARPIN Is Required for Optimal NLRP3 Inflammasome Activation
Prajwal Gurung et al.
JOURNAL OF IMMUNOLOGY (2015)
Expression of the NLRP3 Inflammasome in Carotid Atherosclerosis
Xin Shi et al.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2015)
Estrogen suppresses hepatocellular carcinoma cells through ERβ-mediated upregulation of the NLRP3 inflammasome
Qing Wei et al.
LABORATORY INVESTIGATION (2015)
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Nobuhiko Kayagaki et al.
NATURE (2015)
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
Jianjin Shi et al.
NATURE (2015)
Differential expression of inflammasomes in lung cancer cell lines and tissues
Hui Kong et al.
TUMOR BIOLOGY (2015)
Expression of the NLRP3 Inflammasome in Carotid Atherosclerosis
Xin Shi et al.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES (2015)
Small molecule-driven mitophagy-mediated NLRP3 inflammasome inhibition is responsible for the prevention of colitis-associated cancer
Wenjie Guo et al.
AUTOPHAGY (2014)
FADD and Caspase-8 Mediate Priming and Activation of the Canonical and Noncanonical Nlrp3 Inflammasomes
Prajwal Gurung et al.
JOURNAL OF IMMUNOLOGY (2014)
Transcriptome analysis of human adipocytes implicates the NOD-like receptor pathway in obesity-induced adipose inflammation
Zheng Yin et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2014)
Deregulation of the NLRP3 inflammasome in hepatic parenchymal cells during liver cancer progression
Qing Wei et al.
LABORATORY INVESTIGATION (2014)
Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis
Lieselotte Vande Walle et al.
NATURE (2014)
Ectopic Fat in Insulin Resistance, Dyslipidemia, and Cardiometabolic Disease
Gerald I. Shulman
NEW ENGLAND JOURNAL OF MEDICINE (2014)
The NOD-Like Receptor Signalling Pathway in Helicobacter pylori Infection and Related Gastric Cancer: A Case-Control Study and Gene Expression Analyses
Natalia Castano-Rodriguez et al.
PLOS ONE (2014)
The CARD plays a critical role in ASC foci formation and inflammasome signalling
Martina Proell et al.
BIOCHEMICAL JOURNAL (2013)
Obesity phenotype is related to NLRP3 inflammasome activity and immunological profile of visceral adipose tissue
Nathalie Esser et al.
DIABETOLOGIA (2013)
Deubiquitination of NLRP3 by BRCC3 Critically Regulates Inflammasome Activity
Benedicte F. Py et al.
MOLECULAR CELL (2013)
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation
Frederick J. Sheedy et al.
NATURE IMMUNOLOGY (2013)
Fatty acid-induced mitochondrial uncoupling elicits inflammasome-independent IL-1α and sterile vascular inflammation in atherosclerosis
Stefan Freigang et al.
NATURE IMMUNOLOGY (2013)
Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth
Melanie Bruchard et al.
NATURE MEDICINE (2013)
Diet-Induced Obesity Promotes Colon Tumor Development in Azoxymethane-Treated Mice
Iina Tuominen et al.
PLOS ONE (2013)
NLRP3 Suppresses NK Cell-Mediated Responses to Carcinogen-Induced Tumors and Metastases
Melvyn T. Chow et al.
CANCER RESEARCH (2012)
NLRP3 promotes inflammation-induced skin cancer but is dispensable for asbestos-induced mesothelioma
Melvyn T. Chow et al.
IMMUNOLOGY AND CELL BIOLOGY (2012)
Multiple Binding Sites on the Pyrin Domain of ASC Protein Allow Self-association and Interaction with NLRP3 Protein
Parimala R. Vajjhala et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Toll or Interleukin-1 Receptor (TIR) Domain-containing Adaptor Inducing Interferon-β (TRIF)-mediated Caspase-11 Protease Production Integrates Toll-like Receptor 4 (TLR4) Protein- and Nlrp3 Inflammasome-mediated Host Defense against Enteropathogens
Prajwal Gurung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Genetic inactivation of IL-1 signaling enhances atherosclerotic plaque instability and reduces outward vessel remodeling in advanced atherosclerosis in mice
Matthew R. Alexander et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
Samuel Huber et al.
NATURE (2012)
Inflammasome polymorphisms confer susceptibility to sporadic malignant melanoma
Deepti Verma et al.
PIGMENT CELL & MELANOMA RESEARCH (2012)
Lack of Interleukin-1 Receptor I (IL-1RI) Protects Mice From High-Fat Diet Induced Adipose Tissue Inflammation Coincident With Improved Glucose Homeostasis
Fiona C. McGillicuddy et al.
DIABETES (2011)
Cytokines Tumor Necrosis Factor-α and Interferon-γ Induce Pancreatic β-Cell Apoptosis through STAT1-mediated Bim Protein Activation
Jenny Barthson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Inflammatory links between obesity and metabolic disease
Carey N. Lumeng et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Non-canonical inflammasome activation targets caspase-11
Nobuhiko Kayagaki et al.
NATURE (2011)
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
Haitao Wen et al.
NATURE IMMUNOLOGY (2011)
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
Bolormaa Vandanmagsar et al.
NATURE MEDICINE (2011)
Inflammasome is a central player in the induction of obesity and insulin resistance
Rinke Stienstra et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome
P. Menu et al.
CELL DEATH & DISEASE (2011)
Engagement of Fatty Acids With Toll-like Receptor 2 Drives Interleukin-1β Production via the ASC/Caspase 1 Pathway in Monosodium Urate Monohydrate Crystal-Induced Gouty Arthritis
Leo A. B. Joosten et al.
ARTHRITIS AND RHEUMATISM (2010)
The Inflammasome Component Nlrp3 Impairs Antitumor Vaccine by Enhancing the Accumulation of Tumor-Associated Myeloid-Derived Suppressor Cells
Hendrik W. van Deventer et al.
CANCER RESEARCH (2010)
Pattern Recognition Receptors and Inflammation
Osamu Takeuchi et al.
CELL (2010)
The Inflammasome-Mediated Caspase-1 Activation Controls Adipocyte Differentiation and Insulin Sensitivity
Rinke Stienstra et al.
CELL METABOLISM (2010)
The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis
Md. Hasan Zaki et al.
IMMUNITY (2010)
Constitutively Active Inflammasome in Human Melanoma Cells Mediating Autoinflammation via Caspase-1 Processing and Secretion of Interleukin-1β
Miyako Okamoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
Irving C. Allen et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
IL-18 Production Downstream of the Nlrp3 Inflammasome Confers Protection against Colorectal Tumor Formation
Mohammad Hasan Zaki et al.
JOURNAL OF IMMUNOLOGY (2010)
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
Peter Duewell et al.
NATURE (2010)
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1 beta in type 2 diabetes
Seth L. Masters et al.
NATURE IMMUNOLOGY (2010)
Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4
Bo Hu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Differential requirement for the activation of the inflammasome for processing and release of IL-1β in monocytes and macrophages
Mihai G. Netea et al.
BLOOD (2009)
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
Franz G. Bauernfeind et al.
JOURNAL OF IMMUNOLOGY (2009)
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β-dependent adaptive immunity against tumors
Francois Ghiringhelli et al.
NATURE MEDICINE (2009)
Overexpression of Interleukin-1β Induces Gastric Inflammation and Cancer and Mobilizes Myeloid-Derived Suppressor Cells in Mice
Shuiping Tu et al.
CANCER CELL (2008)
Origin and physiological roles of inflammation
Ruslan Medzhitov
NATURE (2008)
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
Annett Halle et al.
NATURE IMMUNOLOGY (2008)
ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1β and IL-18 secretion in an autocrine way
Alessandra Piccini et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression
Stephanie K. Bunt et al.
CANCER RESEARCH (2007)
Metabolic endotoxemia initiates obesity and insulin resistance
Patrice D. Cani et al.
DIABETES (2007)
Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response
J. Alain Kummer et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2007)
Interleukin-1 beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression
Jennifer Jager et al.
ENDOCRINOLOGY (2007)
Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3
TD Kanneganti et al.
NATURE (2006)
Cryopyrin activates the inflammasome in response to toxins and ATP
S Mariathasan et al.
NATURE (2006)
Gout-associated uric acid crystals activate the NALP3 inflammasome
F Martinon et al.
NATURE (2006)
Molecular basis of the spectral expression of CIAS1 mutations associated with phagocytic cell-mediated autoinflammatory disorders CINCA/NOMID, MWS, and FCU
B Neven et al.
BLOOD (2004)
Cytokines in cancer pathogenesis and cancer therapy
G Dranoff
NATURE REVIEWS CANCER (2004)