4.6 Article

Functional Connectomics and Disease Progression in Drug-Naive Parkinson's Disease Patients

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Summary: Longitudinal connectivity studies in Parkinson's disease patients at different stages reveal varying brain network functional alterations, with RS fMRI changes associated with motor, cognitive, and non-motor evolution. RS fMRI may serve as an early biomarker for PD motor and non-motor progression, predicting clinical deterioration.

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