Recent studies have provided evidence that the human NLRP1 inflammasome can be activated by two chemically and mechanistically distinct signals, challenging the previous notion that it evolved to detect and respond to a single danger-associated molecular pattern like other mammalian inflammasomes.
Recent studies provide evidence that two chemically and mechanistically distinct signals activate the human NLRP1 inflammasome, challenging the concept that it-like other mammalian inflammasomes characterized thus far-evolved to detect and respond to a single danger-associated molecular pattern.
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