期刊
MOLECULAR AND CELLULAR BIOCHEMISTRY
卷 476, 期 7, 页码 2739-2752出版社
SPRINGER
DOI: 10.1007/s11010-021-04120-6
关键词
Alzheimer’ s disease; Parkinson’ s disease; Therapeutic management; Neurodegenerative diseases; Neurodegeneration
类别
资金
- National Medicinal Plants Board, Ministry of AYUSH, Government of India [Z. 18017/187/CSS/R&D/DL-01/2019-20-NMPB-IVA]
Neurodegeneration is a significant contributor to morbidity, mortality, and cognitive impairment in aging populations. This review focuses on the biological and psychosocial risk factors associated with Alzheimer's and Parkinson's diseases, and highlights the importance of current therapeutic strategies in improving quality of life for patients.
Neurodegeneration is a prevalent and one of the emerging reasons for morbidity, mortality, and cognitive impairment in aging. Dementia is one of such conditions of neurodegeneration, partially manageable, irreversible, and worsens over time. This review is focused on biological and psychosocial risk factors associated with Alzheimer's and Parkinson's diseases, highlighting the value of cognitive decline. We further emphasized on current therapeutic strategies from pharmacological and non-pharmacological perspectives focusing on their effects on cognitive impairment, protein aggregation, tau pathology, and improving the quality of life. Deeper mechanistic insights into the multifactorial neurodegeneration could offer the design and development of promising diagnostic and therapeutic strategies.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据