期刊
MEDICINE
卷 100, 期 10, 页码 -出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MD.0000000000024823
关键词
bleeding; children; double-balloon enteroscopy; Meckel's diverticulum; safety; surgical operation
Retrospective review and analysis on 10 cases of children with Meckel's diverticula (MD) bleeding revealed that preoperative double-balloon enteroscopy (DBE) is a safe method with diagnostic and treatment values for children’s MD, providing valuable guidance for surgical treatment.
The diagnostic and treatment values and safety of preoperative double-balloon enteroscopy (DBE) for Meckel's diverticula (MD) bleeding in children by retrospective review and analyses. The clinical data were collected and analyzed from 10 cases of children with MD receiving preoperative DBE examination and postoperative pathological confirmation. The diagnostic and treatment values and safety were assessed through the comparison of the DBE results and intra-operative observations and subsequently postoperative pathological results. Total cases are 10, 7 males and 3 females. The male to female ratio is 2.3 to 1. The youngest patient is 3.3 years old and oldest 12.1, the average age is 7.4 +/- 3.0. The lowest body weight is 12.6kg and the average is 32.5 +/- 18.9 kg. The hematochezia was the main clinical manifestation in all patients with anemia and moderate to severe anemia were common (9/10, 90%). All patients had and tolerated the DBE procedures via anal route with 100% success rate. There were no observable complications during the examinations and post operations. All patients were diagnosed with MD by DBE. Exploratory laparoscopy and surgical operations were subsequently performed. All surgical samples were confirmed by pathology as bleeding MD. The postoperative follow-ups up to April 2019 (from 3 to 12 months) do not show any bleeding sign. Pathological examinations found ectopic gastric mucosa in 9 patients (90%) and one case had both ectopic gastric mucosa pancreatic tissue (10%). The distance of MD to ileocecal valve was from 60 to 100cm (average 81.0 +/- 16.0 cm) by DBE examinations. Surgery showed similar findings from 30 to 100cm (average 71.0 +/- 18.5) consistently to DBE. There is no statistical significance between 2 methods (Z = 1.715, P=.086). DBE examination proves to be a safe method for diagnosing children's MD disease and can reliably determine the bleeding lesions in children's MD, providing valuable guidance for surgical treatment of children's MD bleeding.
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