期刊
MEDICINE
卷 100, 期 7, 页码 -出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MD.0000000000024624
关键词
diagnosis; kawasaki disease; neonate; newborn
资金
- National Natural Science Foundation of China (NSFC) [81771626, 81971423]
- Jiangsu Provincial Department of Science and Technology Key R&D Program (Social Development) project [BE2020658]
- Jiangsu Provincial Maternal and Child Health Key Talents Project [FRC201731]
- Project of Science and Technology Development Plan of Suzhou [SS201428]
- Diagnosis and Treatment Technology Project of Clinical Key Diseases in Suzhou province [LCZX201612]
- Minsheng Technology -Key Technology Application Research Project [SS201644]
Neonatal Kawasaki Disease is extremely rare, with atypical clinical manifestations that are easy to miss. Early diagnosis and treatment are crucial to prevent potentially serious complications.
Rationale: Kawasaki Disease (KD) is a self-limiting and acute systemic vasculitis of childhood that leads to coronary artery abnormality in about 25% of untreated cases. KD is extremely rare in neonates. The purpose of this paper is to explore the clinical features and diagnosis and treatment of Neonatal Kawasaki Disease for early identification. Patient concerns: A 24-day-old male with 3 hours fever and a rash was admitted to our hospital. Diagnoses: He had a fever, rash, cracking of lips, lymph node enlargement in the neck, and distal extremity desquamation. Interventions: The patient was given intravenous immunoglobulin and aspirin with no complications. Outcomes: After discharge, the patient was followed up to 1 year old, with good prognosis and no carditis or coronary artery abnormalities. Lessons: Neonatal Kawasaki disease is extremely rare, and its clinical manifestation is not typical and easy to be missed. If not treated early, it will potentially give rise to coronary artery aneurysms or expansion, ischemic heart disease, and sudden death. Early diagnosis and treatment are very important.
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