4.7 Article

COVID-AL: The diagnosis of COVID-19 with deep active learning

期刊

MEDICAL IMAGE ANALYSIS
卷 68, 期 -, 页码 -

出版社

ELSEVIER
DOI: 10.1016/j.media.2020.101913

关键词

COVID-19; Deep active learning; Computer-aided diagnosis; Sample diversity; Predicted loss

资金

  1. National Key R&D Program of China [2019YFE0190500]
  2. Natural Science Founda-tion of Shanghai , China [20ZR1420400]
  3. State Key Program of National Natural Science Foundation of China [61936001]
  4. Shanghai Science and Technology Foundation [18010500600]
  5. 111 Project [D20031]

向作者/读者索取更多资源

The weakly-supervised deep active learning framework COVID-AL is proposed for diagnosing COVID-19, which can efficiently diagnose COVID-19 and outperforms existing active learning methods in the diagnosis.
The efficient diagnosis of COVID-19 plays a key role in preventing the spread of this disease. The computer-aided diagnosis with deep learning methods can perform automatic detection of COVID-19 using CT scans. However, large scale annotation of CT scans is impossible because of limited time and heavy burden on the healthcare system. To meet the challenge, we propose a weakly-supervised deep active learning framework called COVID-AL to diagnose COVID-19 with CT scans and patient-level labels. The COVID-AL consists of the lung region segmentation with a 2D U-Net and the diagnosis of COVID-19 with a novel hybrid active learning strategy, which simultaneously considers sample diversity and predicted loss. With a tailor-designed 3D residual network, the proposed COVID-AL can diagnose COVID-19 efficiently and it is validated on a large CT scan dataset collected from the CC-CCII. The experimental results demonstrate that the proposed COVID-AL outperforms the state-of-the-art active learning approaches in the diagnosis of COVID-19. With only 30% of the labeled data, the COVID-AL achieves over 95% accuracy of the deep learning method using the whole dataset. The qualitative and quantitative analysis proves the effectiveness and efficiency of the proposed COVID-AL framework. (c) 2020 Elsevier B.V. All rights reserved.

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