Synthesis and characterization of anti-adhesion tricomposite electrospun nanofiber barrier membrane for use in post-surgical adhesion conditions

Adhesion formation is a crucial post-surgical problem that needs to be addressed by clinicians. In this study, we report the synthesis of a novel tricomposite electrospun nanofiber membrane as a potential barrier for the prevention of post-surgical adhesion. The synthesized membrane was characterized using suitable techniques. The membrane showed excellent hydrophilicity (15.2 degrees contact angle), mechanical stability (5.04 MPa with a strain of 50%) and biocompatibility (cell viability of 106%) required for a potential barriers membrane to be used in post adhesion surgical condition. This membrane can be an alternative membrane to address the drawbacks of currently used antiadhesion barrier membrane. (c) 2020 Elsevier B.V. All rights reserved.

Automated summary

The novel tricomposite electrospun nanofiber membrane synthesized in this study exhibits excellent hydrophilicity, mechanical stability, and biocompatibility, making it a potential barrier for preventing post-surgical adhesion. This membrane could serve as an alternative to address the drawbacks of currently used antiadhesion barrier membranes.