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Genomic Characterization of a Novel SARS-CoV-2 Lineage from Rio de Janeiro, Brazil

JOURNAL OF VIROLOGY (2021)

Three-quarters attack rate of SARS-CoV-2 in the Brazilian Amazon during a largely unmitigated epidemic

Lewis F. Buss et al.

Summary: Research indicates that the attack rate of COVID-19 in Manaus, the capital of Amazonas state in northern Brazil, reached 66% in June 2020, rising to 76% by October, higher than the estimated attack rate of 29% in Sao Paulo, southeastern Brazil, during the same period.

SCIENCE (2021)

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Article Microbiology

Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies

Allison J. Greaney et al.

Summary: The evolution of SARS-CoV-2 may impact the recognition of the virus by human antibody-mediated immunity, with mutations affecting antibody binding varying significantly among individuals and within the same individual over time. Despite this variability, mutations that greatly reduce antibody binding usually occur at specific sites in the RBD, with E484 being the most crucial. These findings can inform surveillance efforts for SARS-CoV-2 evolution in the future.

CELL HOST & MICROBE (2021)

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Letter Immunology

Genomic Evidence of SARS-CoV-2 Reinfection Involving E484K Spike Mutation, Brazil

Carolina Kymie Vasques Nonaka et al.

Summary: The case of reinfection from distinct virus lineages in Brazil with the E484K mutation raises concerns about the duration of protective immune responses against SARS-CoV-2, especially with the variant associated with escape from neutralizing antibodies. This highlights potential challenges for virus control measures.

EMERGING INFECTIOUS DISEASES (2021)

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Article Biochemistry & Molecular Biology

IQ-TREE 2: New Models and Efficient Methods for Phylogenetic Inference in the Genomic Era

Bui Quang Minh et al.

MOLECULAR BIOLOGY AND EVOLUTION (2020)

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Article Evolutionary Biology

Posterior Summarization in Bayesian Phylogenetics Using Tracer 1.7

Andrew Rambaut et al.

SYSTEMATIC BIOLOGY (2018)

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Article Virology

Bayesian phylogenetic and phylodynamic data integration using BEAST 1.10

Marc A. Suchard et al.

VIRUS EVOLUTION (2018)

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Genomic Characterization of a Novel SARS-CoV-2 Lineage from Rio de Janeiro, Brazil

相关参考文献

Three-quarters attack rate of SARS-CoV-2 in the Brazilian Amazon during a largely unmitigated epidemic

Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies

Genomic Evidence of SARS-CoV-2 Reinfection Involving E484K Spike Mutation, Brazil

IQ-TREE 2: New Models and Efficient Methods for Phylogenetic Inference in the Genomic Era

Posterior Summarization in Bayesian Phylogenetics Using Tracer 1.7

Bayesian phylogenetic and phylodynamic data integration using BEAST 1.10

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