4.5 Review

Comprehensive two-dimensional gas chromatography as a boosting technology in food-omic investigations

期刊

JOURNAL OF SEPARATION SCIENCE
卷 44, 期 8, 页码 1592-1611

出版社

WILEY-V C H VERLAG GMBH
DOI: 10.1002/jssc.202100017

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comprehensive two‐ dimensional gas chromatography; food metabolomics; food safety; nutrimetabolomics; sensomics

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This review highlights the role of comprehensive two-dimensional gas chromatography in food-omics research, showcasing how it has introduced new concepts and tools for analyzing complex biological samples.
This review focuses on the role that comprehensive two-dimensional gas chromatography can play within the investigation workflows of food-omics and related disciplines and subdisciplines, including food metabolomics, nutrimetabolomics, sensomics, and food safety. After a short introductory survey, discussing the intriguing context of system biology and integrationist approaches of investigation, the concepts of analytical dimensions and the key characteristics of comprehensive two-dimensional gas chromatography are introduced. Through a selection of relevant examples, the boosting role of comprehensive two-dimensional gas chromatography within food-omics is described, providing to the reader evidence of how comprehensive multidimensional separations based platforms have introduced new concepts and tools in the analytical measurement of complex biological samples.

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