期刊
JOURNAL OF PARASITOLOGY
卷 107, 期 2, 页码 179-181出版社
ALLEN PRESS INC
DOI: 10.1645/20-107
关键词
Toxoplasma gondii; Mice; Antibody titer; Brain cysts; Parasite burden; China
类别
资金
- Application and Demonstration of Product Quality and Safety Assurance Technology in Aquaculture Industry [2019YFC1605700]
- Key research projects of Henan higher education institutions [21A230009]
- China Postdoctoral Science Foundation [2016M600577]
This study documented the antibody responses, tissue cyst burden, and mouse virulence of Toxoplasma gondii strains isolated from different hosts in China. All T. gondii strains were found to form tissue cysts in the brains of mice, and the presence of tissue cysts positively correlated with antibody titers against T. gondii. These results may assist in the diagnosis and characterization of T. gondii isolates.
Toxoplasma gondii is an obligate intracellular parasite that has a worldwide distribution and can infect almost all warm-blood animals. Serological tests are the main detection methods for T. gondii infection in animals and humans. Little is known of biological behavior, antibody responses, and virulence of T. gondii strains in mice from China. Here we document antibody responses, tissue cyst burden, and mouse virulence of T. gondii strains isolated from different hosts in China. All T. gondii strains formed tissue cysts in the brains of mice and positively correlated with the T. gondii antibody titer (R-2 = 0.3345). These results should aid in the diagnosis and characterization of T. gondii isolates.
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